CAJ | 학술논문

目的：探讨美沙酮疗效及其副作用对于美沙酮维持治疗（MMT）脱失率的影响。方法以2006年9月至2007年10月在南昌市东湖区和西湖区两个MMT门诊就诊者705例为研究对象，采用问卷调查方法，用Cox回归模型进行分析。结果单因素Cox分析显示：影响MMT脱失的因素为吃饭比原来好、体重增加和皮疹。多因素Cox回归分析显示：吃饭比原来好时脱失者少，而出现皮疹的美沙酮受治者脱失率明显增高。结论 MMT不仅是一项单纯的给服美沙酮工作，更应多了解就诊者的主观感受和客观身体状况，进行切实有效的咨询和干预，从而减少脱失率。
목적：탐토미사동료효급기부작용대우미사동유지치료（MMT）탈실솔적영향。방법이2006년9월지2007년10월재남창시동호구화서호구량개MMT문진취진자705례위연구대상，채용문권조사방법，용Cox회귀모형진행분석。결과단인소Cox분석현시：영향MMT탈실적인소위흘반비원래호、체중증가화피진。다인소Cox회귀분석현시：흘반비원래호시탈실자소，이출현피진적미사동수치자탈실솔명현증고。결론 MMT불부시일항단순적급복미사동공작，경응다료해취진자적주관감수화객관신체상황，진행절실유효적자순화간예，종이감소탈실솔。
Objective To investigate the effects and side effects of methadone on the loss of drug addicts at methadone main-tenance treatment (MMT) outpatient. Methods From September 2006 to October 2007,705 drug addicts who had participated two MMT outpatient departments of Donghu and Xihu district in Nanchang city were investigated with questionnaire. Cox regression was used to analyze influence of effects and side effects of methadone on the loss of MMT drug addicts. Results The single factor Cox regression analysis suggested that appetite,weight gain,and skin rash could influence the loss of MMT patients. The further multivariate factor Cox regression showed that a good appetite could reduce the loss of patients ,and more patients would escape from MMT outpatient because of skin rash. Conclusion MMT is not a simple job as just giving methadone. The physical and men-tal situation of patients should be more appreciated,and then we could carry out more effective consultation and intervention to re-duce the loss of patients.