CAJ | 학술논문

目的：探讨联合应用氨氯地平和卡托普利治疗冠心病合并高血压的临床疗效。方法：将100例冠心病合并高血压患者平均分为观察组和对照组，为观察组患者用氨氯地平和卡托普利进行治疗，为对照组患者使用氢氯噻嗪、尼群地平片等传统药物进行治疗，在用药2个月后比较观察两组患者血压、心绞痛、心电图的变化。结果：经过2个月的用药治疗，两组患者的血压、心绞痛、心电图检查结果相比较差异显著，P<0.05，有统计学意义。与对照组患者相比，观察组患者在进行药物治疗后其冠心病、高血压得到了更好的控制，心电图检查结果得到了更明显的改善，发生不良反应的几率更低，差异显著（P<0.05）,有统计学意义。结论：联合应用氨氯地平和卡托普利治疗冠心病合并高血压疗效确切，安全性高，值得在临床上推广使用。
목적：탐토연합응용안록지평화잡탁보리치료관심병합병고혈압적림상료효。방법：장100례관심병합병고혈압환자평균분위관찰조화대조조，위관찰조환자용안록지평화잡탁보리진행치료，위대조조환자사용경록새진、니군지평편등전통약물진행치료，재용약2개월후비교관찰량조환자혈압、심교통、심전도적변화。결과：경과2개월적용약치료，량조환자적혈압、심교통、심전도검사결과상비교차이현저，P<0.05，유통계학의의。여대조조환자상비，관찰조환자재진행약물치료후기관심병、고혈압득도료경호적공제，심전도검사결과득도료경명현적개선，발생불량반응적궤솔경저，차이현저（P<0.05）,유통계학의의。결론：연합응용안록지평화잡탁보리치료관심병합병고혈압료효학절，안전성고，치득재림상상추엄사용。
objective to amlodipine in combination with captopril observed the curative effect of treatment of coronary heart disease and high blood pressure), confirmed its function. Methods select 100 cases of patients with coronary heart disease and high blood pressure, average divided into observation group and control group. Observation group taking ammonia chloride and captopril, the control group take old drugs. 2 months after observing two groups of the change of blood pressure, angina pectoris, electrocardiogram, and comparison.Results the observation group compared with patients in the control group in blood pressure, angina pectoris and electrocardiogram (ecg) are improved substantially. Conclusion amlodipine in combination with enalapril therapy of coronary heart disease and high blood pressure has significant curative effect, is worth popularizing in clinical use.