实用临床医药杂志
實用臨床醫藥雜誌
실용림상의약잡지
JOURNAL OF JIANGSU CLINICAL MEDICINE
2014年
7期
147-148,151
,共3页
子痫前期%超敏C反应蛋白%白介素-6%肿瘤坏死因子-α
子癇前期%超敏C反應蛋白%白介素-6%腫瘤壞死因子-α
자간전기%초민C반응단백%백개소-6%종류배사인자-α
eclampsism%high-sensitivity C reaction protein%interleukin-6%tumor necro-sis factor-α
目的:探讨子痫前期患者炎症反应在子痫前期进展中的表达及意义。方法选取子痫前期患者100例(子痫前期组),其中轻度子痫前期40例,重度子痫前期60例。另选择健康孕妇60例作为对照组。测定并比较2组血清 hs-CRP、IL-6、TNF-α水平。结果子痫前期组 IL-6、hs-CRP 及 TNF-α水平显著高于对照组,差异有统计学意义(P <0.05),且重度子痫前期患者 IL-6、hs-CRP 及 TNF-α水平显著高于轻度子痫前期患者,差异也有统计学意义(P <0.05)。结论子痫前期患者不仅存在过度的炎症反应,而且随病情进展而加重,早期干预血脂异常可能有助于控制子痫前期的发生和发展。
目的:探討子癇前期患者炎癥反應在子癇前期進展中的錶達及意義。方法選取子癇前期患者100例(子癇前期組),其中輕度子癇前期40例,重度子癇前期60例。另選擇健康孕婦60例作為對照組。測定併比較2組血清 hs-CRP、IL-6、TNF-α水平。結果子癇前期組 IL-6、hs-CRP 及 TNF-α水平顯著高于對照組,差異有統計學意義(P <0.05),且重度子癇前期患者 IL-6、hs-CRP 及 TNF-α水平顯著高于輕度子癇前期患者,差異也有統計學意義(P <0.05)。結論子癇前期患者不僅存在過度的炎癥反應,而且隨病情進展而加重,早期榦預血脂異常可能有助于控製子癇前期的髮生和髮展。
목적:탐토자간전기환자염증반응재자간전기진전중적표체급의의。방법선취자간전기환자100례(자간전기조),기중경도자간전기40례,중도자간전기60례。령선택건강잉부60례작위대조조。측정병비교2조혈청 hs-CRP、IL-6、TNF-α수평。결과자간전기조 IL-6、hs-CRP 급 TNF-α수평현저고우대조조,차이유통계학의의(P <0.05),차중도자간전기환자 IL-6、hs-CRP 급 TNF-α수평현저고우경도자간전기환자,차이야유통계학의의(P <0.05)。결론자간전기환자불부존재과도적염증반응,이차수병정진전이가중,조기간예혈지이상가능유조우공제자간전기적발생화발전。
Objective To explore the expression and significance of inflammatory reaction in patients with progress of eclampsism.Methods 100 patients with eclampsism were designed as eclampsism group,which including 40 cases of mild eclampsism and 60 cases of severe eclampsism. 60 healthy pregnant women were designed as control group.Levels of IL-6,hs-CRP and TNF-αwere detected and compared between two groups.Results Levels of IL-6,hs-CRP and TNF-αin eclampsism group were significantly higher than those in control group (P <0.05),and levels of in-dexes mentioned above in severe eclampsism group were significantly higher than those in mild eclampsism group as well (P <0.05).Conclusion Excessive inflammatory reaction can be ob-served in patients with eclampsism.Early intervention on abnormal blood fat level may help control the occurrence and development of eclampsism.