实用临床医药杂志
實用臨床醫藥雜誌
실용림상의약잡지
JOURNAL OF JIANGSU CLINICAL MEDICINE
2014年
7期
14-16
,共3页
急性脑梗死%颈动脉粥样硬化斑块%尿酸%高敏C反应蛋白%脂蛋白(a)
急性腦梗死%頸動脈粥樣硬化斑塊%尿痠%高敏C反應蛋白%脂蛋白(a)
급성뇌경사%경동맥죽양경화반괴%뇨산%고민C반응단백%지단백(a)
acute cerebral infarction%carotid atherosclerosis plaque%uric acid%high-sensi-tivity c-reactive protein%lipoprotein(a)
目的：探讨急性脑梗死患者血清尿酸（SUA）、高敏 C 反应蛋白（hs-CRP）及脂蛋白（LP）（a）与颈动脉粥样硬化斑块的关系。方法选取64例急性脑梗死患者，根据彩色多普勒超声（CDU）检测结果将颈动脉粥样硬化的程度分为 A 组、B 组及 C 组。分别测定 SUA、hs-CRP 及 LP（a）在各组血清中的浓度变化，对其结果进行统计分析。结果随着内膜中层厚度增加， SUA、hs-CRP 及 LP（a）水平相应升高，3组间比较差异有统计学意义。B、C 组患者 SUA 与 hs-CRP、LP（a）呈显著正相关；hs-CRP 与 LP（a）呈显著正相关。结论急性脑梗死患者 SUA、hs-CRP 及 LP（a）水平变化与颈动脉粥样硬化程度呈正相关，3者之间相互作用参与促进动脉粥样硬化的发生发展过程。
目的：探討急性腦梗死患者血清尿痠（SUA）、高敏 C 反應蛋白（hs-CRP）及脂蛋白（LP）（a）與頸動脈粥樣硬化斑塊的關繫。方法選取64例急性腦梗死患者，根據綵色多普勒超聲（CDU）檢測結果將頸動脈粥樣硬化的程度分為 A 組、B 組及 C 組。分彆測定 SUA、hs-CRP 及 LP（a）在各組血清中的濃度變化，對其結果進行統計分析。結果隨著內膜中層厚度增加， SUA、hs-CRP 及 LP（a）水平相應升高，3組間比較差異有統計學意義。B、C 組患者 SUA 與 hs-CRP、LP（a）呈顯著正相關；hs-CRP 與 LP（a）呈顯著正相關。結論急性腦梗死患者 SUA、hs-CRP 及 LP（a）水平變化與頸動脈粥樣硬化程度呈正相關，3者之間相互作用參與促進動脈粥樣硬化的髮生髮展過程。
목적：탐토급성뇌경사환자혈청뇨산（SUA）、고민 C 반응단백（hs-CRP）급지단백（LP）（a）여경동맥죽양경화반괴적관계。방법선취64례급성뇌경사환자，근거채색다보륵초성（CDU）검측결과장경동맥죽양경화적정도분위 A 조、B 조급 C 조。분별측정 SUA、hs-CRP 급 LP（a）재각조혈청중적농도변화，대기결과진행통계분석。결과수착내막중층후도증가， SUA、hs-CRP 급 LP（a）수평상응승고，3조간비교차이유통계학의의。B、C 조환자 SUA 여 hs-CRP、LP（a）정현저정상관；hs-CRP 여 LP（a）정현저정상관。결론급성뇌경사환자 SUA、hs-CRP 급 LP（a）수평변화여경동맥죽양경화정도정정상관，3자지간상호작용삼여촉진동맥죽양경화적발생발전과정。
Objective To explore the relationship between carotid atherosclerosis and serum uric acid (SUA),high-sensitivity c-reactive protein (hs-CRP)and lipoprotein (LP)(a)in patients with acute cerebral infarction (ACI).Methods According to the carotid atherosclerosis degrees de-tected by color doppler ultrasound (CDU),64 patients with ACI were divided into groups A,group B and group C.The changes of SUA,hs-CRP and LP(a)concentrations were respectively detected and analyzed in all the groups.Results With the increasing of intima-media thickness,the levels of SUA,hs-CRP and LP(a)went up,and there were significant differences among the three groups. In group B and group C,SUA was positively associated with hs-CRP and LP(a),and hs-CRP was positively associated with LP(a).Conclusion The levels of SUA,hs-CRP and LP(a)are positive-ly associated with carotid atherosclerosis degrees in patients with ACI,and their mutual action par-ticipates in the formation and progression of atherosclerosis.
