中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
29期
34-35
,共2页
丙型肝炎病毒抗体%丙型肝炎病毒核糖核酸%丙型肝炎%PCR-荧光探针
丙型肝炎病毒抗體%丙型肝炎病毒覈糖覈痠%丙型肝炎%PCR-熒光探針
병형간염병독항체%병형간염병독핵당핵산%병형간염%PCR-형광탐침
Antibody to hepatitis C virus%Hepatitis C virus ribonucleic acid%Hepatitis C%PCR-fluorescence probe
目的：探讨丙型肝炎病毒抗体(抗-HCV)和丙型肝炎病毒核糖核酸(HCV-RNA)定量联合检测结果对丙型肝炎确诊的临床意义。方法对258例ELISA法检测的血清抗-HCV阳性丙型肝炎(HC)患者，同时采用PCR-荧光探针法检测其HCV-RNA含量。结果258例抗-HCV阳性丙型肝炎患者中HCV-RNA阴性92例，占35.66%；17例HCV-RNA弱阳性，占6.59%；HCV-RNA阳性149例，即57.75%的HC患者存在病毒血症。结论ELISA法联合检测抗-HCV和HCV-RNA有助于丙型肝炎确诊病毒血症以及监控HCV的感染，并及时进行抗病毒治疗。
目的：探討丙型肝炎病毒抗體(抗-HCV)和丙型肝炎病毒覈糖覈痠(HCV-RNA)定量聯閤檢測結果對丙型肝炎確診的臨床意義。方法對258例ELISA法檢測的血清抗-HCV暘性丙型肝炎(HC)患者，同時採用PCR-熒光探針法檢測其HCV-RNA含量。結果258例抗-HCV暘性丙型肝炎患者中HCV-RNA陰性92例，佔35.66%；17例HCV-RNA弱暘性，佔6.59%；HCV-RNA暘性149例，即57.75%的HC患者存在病毒血癥。結論ELISA法聯閤檢測抗-HCV和HCV-RNA有助于丙型肝炎確診病毒血癥以及鑑控HCV的感染，併及時進行抗病毒治療。
목적：탐토병형간염병독항체(항-HCV)화병형간염병독핵당핵산(HCV-RNA)정량연합검측결과대병형간염학진적림상의의。방법대258례ELISA법검측적혈청항-HCV양성병형간염(HC)환자，동시채용PCR-형광탐침법검측기HCV-RNA함량。결과258례항-HCV양성병형간염환자중HCV-RNA음성92례，점35.66%；17례HCV-RNA약양성，점6.59%；HCV-RNA양성149례，즉57.75%적HC환자존재병독혈증。결론ELISA법연합검측항-HCV화HCV-RNA유조우병형간염학진병독혈증이급감공HCV적감염，병급시진행항병독치료。
Objective To investigate the clinical significance of hepatitis C virus antibody (anti-HCV) combined with hepatitis C virus ribonucleic acid (HCV-RNA) quantitative detection in the diagnosis of hepatitis C (HC).Methods A total of 258 cases of HC with anti-HCV positive were detected by ELISA method and PCR-fluorescence probe for the HCV-RNA content.Results Among the 258 cases with anti-HCV positive, there were 92 cases of HCV-RNA negative as 35.66%, 17 cases of HCV-RNA weakly positive as 6.59%, and 149 cases of HCV-RNA positive. Thus, there were 57.75% of the HC patients with viremia.Conclusion ELISA method in combined detection of anti-HCV and HCV-RNA helps to diagnose viremia of HC, monitor HCV infection and conduct timely antiviral treatment.
