CAJ | 학술논문

类风湿关节炎是以慢性对称性多关节滑膜炎、骨及软骨破坏为主要特征的自身免疫性疾病，其发展过程中的骨代谢异常可导致不同程度骨量丢失和骨破坏，骨破坏的相关指标可反映骨量丢失的严重程度，并可预测疾病发展和关节破坏程度。本文对类风湿关节炎患者骨吸收相关指标与关节破坏相关性的最新进展进行综述。
류풍습관절염시이만성대칭성다관절활막염、골급연골파배위주요특정적자신면역성질병，기발전과정중적골대사이상가도치불동정도골량주실화골파배，골파배적상관지표가반영골량주실적엄중정도，병가예측질병발전화관절파배정도。본문대류풍습관절염환자골흡수상관지표여관절파배상관성적최신진전진행종술。
Rheumatoid arthritis ( RA) is an autoimmune disease mainly characterized by chronic symmetric multi-joint synovitis and destruction of bone and cartilage .In the course of RA , abnormaI bone metaboIism may lead to bone loss of different degrees and bone destruction .Relevant variables for bone destruction can refIect the severity of bone loss, and predict the development of disease and joint destruction .This review focuses on the latest advances in the corre-lation between bone resorption markers and joint damage in RA .