CAJ | 학술논문

[目的]比较复方血竭与庆大霉素联合地塞米松灌肠对放射性直肠炎的疗效。[方法]采用完全随机、三盲方法将187例放射性肠炎患者分为治疗组与对照组；治疗组99例采用复方血竭灌肠液灌肠，对照组88例采用庆大霉素联合地塞米松灌肠，疗程均为20 d；观察2组治疗后临床疗效及内镜评价疗效。[结果]治疗组临床总有效率为88.7％，内镜评价总有效率为88.6％；对照组临床总有效率为75.9％；内镜评价总有效率为72.4％。2组在临床、内镜评价上均差异有统计学意义（ P＜0.05）。[结论]用复方血竭和庆大霉素联合地塞米松灌肠方法治疗放射性直肠炎均有良好疗效，但复方血竭优于庆大霉素联合地塞米松。
[목적]비교복방혈갈여경대매소연합지새미송관장대방사성직장염적료효。[방법]채용완전수궤、삼맹방법장187례방사성장염환자분위치료조여대조조；치료조99례채용복방혈갈관장액관장，대조조88례채용경대매소연합지새미송관장，료정균위20 d；관찰2조치료후림상료효급내경평개료효。[결과]치료조림상총유효솔위88.7％，내경평개총유효솔위88.6％；대조조림상총유효솔위75.9％；내경평개총유효솔위72.4％。2조재림상、내경평개상균차이유통계학의의（ P＜0.05）。[결론]용복방혈갈화경대매소연합지새미송관장방법치료방사성직장염균유량호료효，단복방혈갈우우경대매소연합지새미송。
Objective]To evaluate the curative efficacy and side effects of compound-dracorhodin vs gen-tamicin plus dexamethasone coloclysis for radiation proctitis.[Methods]By randomized tri-blind method ,the treatment group ,total 99 cases ,were treated with Compound-dracorhodin coloclysis.The control group ,to-tal 88 cases ,were treated with Gentamicin plus dexamethasone coloclysis.The curative efficacy and side effects of Compound-dracorhodin vs.Gentamicin plus dexamethasone coloclysis for radiation proctitis were observed ,with a treatment course of 20 days.[Results]After 20-day treatment ,significant differences were noted between the two groups in clinical ,endoscopic response rates(total clinical effective rate of was 86/97 ,endoscopic effective rate was 84/97 in Compound-dracorhodin treatment group vs.66/87 ,63/87 in Gen-tamicin plus dexamethasone group ,P <0.05).[Conclusion]Compound-dracorhodin coloclysis is superior to Gentamicin plus dexamethasone coloclysis in efficacy and mild side-effects for patients with radiation proc-titis.