江西师范大学学报(自然科学版)
江西師範大學學報(自然科學版)
강서사범대학학보(자연과학판)
JOURNAL OF JIANGXI NORMAL UNIVERSITY(NATURAL SCIENCES EDITION)
2014年
3期
314-318,323
,共6页
赵洋%叶兴林%杨琴%刘卫生%彭以元
趙洋%葉興林%楊琴%劉衛生%彭以元
조양%협흥림%양금%류위생%팽이원
CMQ%细胞%群体%微囊藻%蓝藻水华
CMQ%細胞%群體%微囊藻%藍藻水華
CMQ%세포%군체%미낭조%람조수화
CMQ%cell%groups%Microcystis%cyanobacterial blooms
近年来,随着水体富营养化程度加剧,蓝藻水华现象已成为世界性的灾难问题,有效地控制蓝藻水华对于保证水体水质安全和水体生态修复至关重要.喹唑啉类化合物,作为一类生态安全性好且易于降解的生物碱类化合物,具有广谱的抗菌生物活性和药用价值,最近研究发现这类化合物具有潜在的抑制微囊藻生长和控制蓝藻水华的能力.通过2-(4-氯苯基)-4-(4-甲氧基苯基)喹唑啉( CMQ)对群体状的铜绿微囊藻(Microcystis aeruginosa)的生长影响实验,发现CMQ在大于5.0 mg·L-1的浓度条件下,对微囊藻有强烈抑制效果,4 d内CMQ对微囊藻细胞的50%生长抑制浓度( EC50)为1.93 mg·L-1.通过对微囊藻的群体形态和大小的变化观察,结果表明CMQ能够降解M. aeruginosa群体并引起群体颗粒变小,导致明显的群体沉降.
近年來,隨著水體富營養化程度加劇,藍藻水華現象已成為世界性的災難問題,有效地控製藍藻水華對于保證水體水質安全和水體生態脩複至關重要.喹唑啉類化閤物,作為一類生態安全性好且易于降解的生物堿類化閤物,具有廣譜的抗菌生物活性和藥用價值,最近研究髮現這類化閤物具有潛在的抑製微囊藻生長和控製藍藻水華的能力.通過2-(4-氯苯基)-4-(4-甲氧基苯基)喹唑啉( CMQ)對群體狀的銅綠微囊藻(Microcystis aeruginosa)的生長影響實驗,髮現CMQ在大于5.0 mg·L-1的濃度條件下,對微囊藻有彊烈抑製效果,4 d內CMQ對微囊藻細胞的50%生長抑製濃度( EC50)為1.93 mg·L-1.通過對微囊藻的群體形態和大小的變化觀察,結果錶明CMQ能夠降解M. aeruginosa群體併引起群體顆粒變小,導緻明顯的群體沉降.
근년래,수착수체부영양화정도가극,람조수화현상이성위세계성적재난문제,유효지공제람조수화대우보증수체수질안전화수체생태수복지관중요.규서람류화합물,작위일류생태안전성호차역우강해적생물감류화합물,구유엄보적항균생물활성화약용개치,최근연구발현저류화합물구유잠재적억제미낭조생장화공제람조수화적능력.통과2-(4-록분기)-4-(4-갑양기분기)규서람( CMQ)대군체상적동록미낭조(Microcystis aeruginosa)적생장영향실험,발현CMQ재대우5.0 mg·L-1적농도조건하,대미낭조유강렬억제효과,4 d내CMQ대미낭조세포적50%생장억제농도( EC50)위1.93 mg·L-1.통과대미낭조적군체형태화대소적변화관찰,결과표명CMQ능구강해M. aeruginosa군체병인기군체과립변소,도치명현적군체침강.
Along with increasing eutrophication in recent years,massive cyanobacterial blooms have become a severe environmental problem in freshwaters worldwide. Therefore,developing an effective method to control the cyanobac-terial bloom essential to guarantee the water quality security and to recover the aquatic ecosystem. Quinazoline deriv-atives,endowed with a broad spectrum of biological activities and therapeutic properties,had a potential ability to in-hibit the groth of Microcystis and control the cyanobacterial blooms. In this study,it was shown that CMQ could in-tensely inhibit the growth of M. aeruginosa groups at the concentration of higher than 5. 0 mg·L-1 of CMQ,with EC50 for 4 d as 1. 93 mg·L-1. The change of colony morphology and volume size in Microcystis aeruginosa,also suggested that CMQ could break down the M. aeruginosa colonies and cause the smaller size of Microcystis colonies, and led to obvious settlement of these colonies. Based on the results that CMQ had exhibited efficient antialgal activ-ities,it is further implicated that CMQ have apractical application perspective in the control of cyanobacterial blooms.