中国处方药
中國處方藥
중국처방약
CHINA PRESCRIPTION DRUG
2014年
6期
4-6
,共3页
李福雄%甄云%黄振林%陈凯鹏
李福雄%甄雲%黃振林%陳凱鵬
리복웅%견운%황진림%진개붕
颅内压监测%高血压性脑出血%神经功能%二度伤害%药物用量
顱內壓鑑測%高血壓性腦齣血%神經功能%二度傷害%藥物用量
로내압감측%고혈압성뇌출혈%신경공능%이도상해%약물용량
Intracranial pressure%Hypertensive cerebral hemorrhage%Nerve function%Two degree injury%Drug dosage
目的：探讨颅内压（ICP）监测对重症高血压性脑出血患者术后临床疗效、神经功能及药物用量影响。方法将86例重症高血压性脑出血患者按照随机数字表法分为观察组和对照组，每组43例，均行颅血肿清除术。对照组给予术后常规监护，观察组加用ICP监测，比较两组患者的治疗效果、神经功能和脱水药物用量。结果治疗3个月后观察组总有效率为67.44%，对照组为39.53%，两组比较差异有统计学意义（P＜0.05）；观察组术后1周内平均甘露醇用量为（781±76）g，术后1周ICP为（1.72±0.23）kPa，均显著低于对照组，差异有统计学意义（P＜0.05）；术后1周两组患者的神经功能缺损评分均低于术前，观察组为（13.3±2.2）分，低于对照组，差异有统计学意义（P＜0.05）；观察组术后电解质紊乱、肾功能损害发生率为9.30%、4.65%，均低于对照组，差异有统计学意义（P＜0.05）；对照组术后1周血尿素氮及24 h尿蛋白水平均低于观察组，差异均有统计学意义（P＜0.05）。结论通过实施ICP监测可以显著改善患者预后，减少脱水药物用量，减轻对患者神经功能损伤，具有较高的临床价值。
目的：探討顱內壓（ICP）鑑測對重癥高血壓性腦齣血患者術後臨床療效、神經功能及藥物用量影響。方法將86例重癥高血壓性腦齣血患者按照隨機數字錶法分為觀察組和對照組，每組43例，均行顱血腫清除術。對照組給予術後常規鑑護，觀察組加用ICP鑑測，比較兩組患者的治療效果、神經功能和脫水藥物用量。結果治療3箇月後觀察組總有效率為67.44%，對照組為39.53%，兩組比較差異有統計學意義（P＜0.05）；觀察組術後1週內平均甘露醇用量為（781±76）g，術後1週ICP為（1.72±0.23）kPa，均顯著低于對照組，差異有統計學意義（P＜0.05）；術後1週兩組患者的神經功能缺損評分均低于術前，觀察組為（13.3±2.2）分，低于對照組，差異有統計學意義（P＜0.05）；觀察組術後電解質紊亂、腎功能損害髮生率為9.30%、4.65%，均低于對照組，差異有統計學意義（P＜0.05）；對照組術後1週血尿素氮及24 h尿蛋白水平均低于觀察組，差異均有統計學意義（P＜0.05）。結論通過實施ICP鑑測可以顯著改善患者預後，減少脫水藥物用量，減輕對患者神經功能損傷，具有較高的臨床價值。
목적：탐토로내압（ICP）감측대중증고혈압성뇌출혈환자술후림상료효、신경공능급약물용량영향。방법장86례중증고혈압성뇌출혈환자안조수궤수자표법분위관찰조화대조조，매조43례，균행로혈종청제술。대조조급여술후상규감호，관찰조가용ICP감측，비교량조환자적치료효과、신경공능화탈수약물용량。결과치료3개월후관찰조총유효솔위67.44%，대조조위39.53%，량조비교차이유통계학의의（P＜0.05）；관찰조술후1주내평균감로순용량위（781±76）g，술후1주ICP위（1.72±0.23）kPa，균현저저우대조조，차이유통계학의의（P＜0.05）；술후1주량조환자적신경공능결손평분균저우술전，관찰조위（13.3±2.2）분，저우대조조，차이유통계학의의（P＜0.05）；관찰조술후전해질문란、신공능손해발생솔위9.30%、4.65%，균저우대조조，차이유통계학의의（P＜0.05）；대조조술후1주혈뇨소담급24 h뇨단백수평균저우관찰조，차이균유통계학의의（P＜0.05）。결론통과실시ICP감측가이현저개선환자예후，감소탈수약물용량，감경대환자신경공능손상，구유교고적림상개치。
Objective To investigate the effect of intracranial pressure monitoring on the clinical efficacy, neurological function and drug dosage in patients with severe hypertensive cerebral hemorrhage. Methods 86 cases of severe hypertensive cerebral hemorrhage were randomly divided into observation group and control group with 43 cases in each group, underwent cranial hematoma. The control group was given routine postoperative care, while observation group were being treated with intracranial pressure monitoring. Therapeutic effect,nerve function and dehydration drug dosage of two groups were compared. Results After 3 months of treatment in observation group, the total effective rate was 67.44%, 39.53%in the control group, there was significant difference between two groups(P<0.05);observation group after one week per capita mannitol dosage is(781±76)g, one weeks after operation, ICP was(1.72±0.23)kPa, were significantly lower than the control group, the difference is statistically significant(P< 0.05);postoperative neurological function deficit score one weeks in patients of the two groups were lower than those before operation, the observation group was(13.3±2.2), lower than that of the control group, the difference was statistically significant(P< 0.05);The observation group and electrolyte disorders, kidney function damage rate was 9.30%, 4.65%, was lower than the control group, the difference was statistically significant(P<0.05);the control group after 1 weeks, blood urea nitrogen and 24 h urinary protein levels were lower than those in the observation group, the differences were statistically significant(P < 0.05).Conclusion The implementation of ICP monitoring can significantly improve the prognosis of patients, reduce the dehydration drug dosage, reduce the neurological damage, and have a high clinical value.
