CAJ | 학술논문

目的：观察穿心莲内酯磺化物雾化治疗急性加重期慢性阻塞性肺疾病（AECOPD）的临床效果。方法将96例急性加重期COPD患者随机分为干预组和对照组，各48例，治疗7 d后观察比较两组的生活质量评分、血气指标及第1秒用力呼气容积( FEV1)占预计值百分比百分值。结果干预组患者的生活质量评分明显优于对照组，差异有显著性( P<0.05)。治疗后血气分析各指标及FEV1占预计值百分比比较，干预组与对照组相比差异均有统计学意义( P<0.05)。结论穿心莲内酯磺化物雾化吸入治疗COPD急性加重期疗效较好，值得临床推广。
목적：관찰천심련내지광화물무화치료급성가중기만성조새성폐질병（AECOPD）적림상효과。방법장96례급성가중기COPD환자수궤분위간예조화대조조，각48례，치료7 d후관찰비교량조적생활질량평분、혈기지표급제1초용력호기용적( FEV1)점예계치백분비백분치。결과간예조환자적생활질량평분명현우우대조조，차이유현저성( P<0.05)。치료후혈기분석각지표급FEV1점예계치백분비비교，간예조여대조조상비차이균유통계학의의( P<0.05)。결론천심련내지광화물무화흡입치료COPD급성가중기료효교호，치득림상추엄。
Objective To investigate the clinical effect of andrograPholide sulfonate nebulization in treating acute exacerbation of chronic obstructive Pulmonary disease ( AECOPD ) . Methods 96 Patients with AECOPD were randomaly divided into the intervention grouP and the contol grouP, 48 cases in each grouP. Afetr 7 d treatment, the life quality score, blood gas indexes and forced exPiratory volume in 1 s ( FEV1 ) Percentage of Predicted value were observed and comPared between the two grouPs. Resluts The life quality scores in the intervention grouP were significantly suPerior to those in the control grouP with statistically significant difference ( P<0. 05 ) . ComParing the blood gas indexes and FEV1 Percentage of Predicted value after treatment, the difference between the intervention grouP and the control grouP had statistically significant difference ( P<0. 05 ) . Conclusion AndrograPholide sulfonate nebulization has better effect in the treatment of AECOPD and deserves to be clinically Promoted.