中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
11期
160-160,161
,共2页
硫喷妥钠%丙泊酚%无抽搐电休克治疗%认知功能
硫噴妥鈉%丙泊酚%無抽搐電休剋治療%認知功能
류분타납%병박분%무추휵전휴극치료%인지공능
thioPental sodium%ProPofol%MECT%cognitive function
目的：观察无抽搐电休克治疗（MECT）中丙泊酚与硫喷妥钠对抑郁患者血压及认知功能的影响。方法将56例接受MECT治疗的抑郁症患者随机分为两组，在MECT时分别使用硫喷妥钠或丙泊酚诱导麻醉，疗程为8次，在治疗前和治疗结束后5 min记录患者心率（HR）、平均动脉压（MAP），治疗前和疗程结束1周后进行汉密顿抑郁量表（HAMD）、威斯康星卡片分类（WCST）、连续作业测验（CPT）、修订韦氏成人智力量表（WAIS-RC）测查评定。结果硫喷妥钠组MECT后MAP高于丙泊酚组( P<0.01)，两组疗程结束1周后HAMD分均比治疗前降低( P<0.01)，WCST，CPT，WAIS-RC评分比较无统计学差异( P>0.05)。结论丙泊酚用于MECT治疗麻醉诱导时，对患者认知功能无明显影响，同时对MAP影响小，可作为MECT首选麻醉药。
目的：觀察無抽搐電休剋治療（MECT）中丙泊酚與硫噴妥鈉對抑鬱患者血壓及認知功能的影響。方法將56例接受MECT治療的抑鬱癥患者隨機分為兩組，在MECT時分彆使用硫噴妥鈉或丙泊酚誘導痳醉，療程為8次，在治療前和治療結束後5 min記錄患者心率（HR）、平均動脈壓（MAP），治療前和療程結束1週後進行漢密頓抑鬱量錶（HAMD）、威斯康星卡片分類（WCST）、連續作業測驗（CPT）、脩訂韋氏成人智力量錶（WAIS-RC）測查評定。結果硫噴妥鈉組MECT後MAP高于丙泊酚組( P<0.01)，兩組療程結束1週後HAMD分均比治療前降低( P<0.01)，WCST，CPT，WAIS-RC評分比較無統計學差異( P>0.05)。結論丙泊酚用于MECT治療痳醉誘導時，對患者認知功能無明顯影響，同時對MAP影響小，可作為MECT首選痳醉藥。
목적：관찰무추휵전휴극치료（MECT）중병박분여류분타납대억욱환자혈압급인지공능적영향。방법장56례접수MECT치료적억욱증환자수궤분위량조，재MECT시분별사용류분타납혹병박분유도마취，료정위8차，재치료전화치료결속후5 min기록환자심솔（HR）、평균동맥압（MAP），치료전화료정결속1주후진행한밀돈억욱량표（HAMD）、위사강성잡편분류（WCST）、련속작업측험（CPT）、수정위씨성인지역량표（WAIS-RC）측사평정。결과류분타납조MECT후MAP고우병박분조( P<0.01)，량조료정결속1주후HAMD분균비치료전강저( P<0.01)，WCST，CPT，WAIS-RC평분비교무통계학차이( P>0.05)。결론병박분용우MECT치료마취유도시，대환자인지공능무명현영향，동시대MAP영향소，가작위MECT수선마취약。
Objective To investigate the effects of thioPental sodium and ProPofol on BP and the cognitive function in the Patients with dePression during the modified electroconvulsive theraPy ( MECT ) . Methods 56 Patients with major dePression treated by MECT were randomly divided into 2 grouP and Performed the induced anesthesia with thioPental sodium and ProPofol resPectively during MECT. The course of treatment was 8 times. The heart rate ( HR ) and mean arterial Pressure ( MAP ) were recorded before theraPy and at 5 min af-ter MECT. DePression and the cognitive function were evaluated by using the Hamilton DePression Scale ( HAMD ) , the Wisconsin Card Sorting Test ( WCST ) , the Continuous Performance Test ( CPT ) and the Wechsler Adult Intelligence Scale-Revised China ( WAIS-RC ) before treatment and in 1 week after treatment. Results MAP in the thioPental sodium grouP was significanfly higher than that in the ProPofol grouP ( P<0. 01 ) . The HAMD scores in 1 week after theraPy in the two grouPs were significanfly decreased comPare with be-fore theraPy ( P<0. 01 ) . There was no statistical differences in the WCST, CPT, WAIS-RC scores ( P>0. 05 ) . Conclusion ProPofol has no obvious influence on the cognition function and little influence on MAP, and can serve as the first choice of anaesthetic for the in-duction of MECT.
