CAJ | 학술논문

目的：探讨进行介入治疗的肿瘤患者医院感染的高危因素。方法选择2010年1月至2012年12月介入治疗肿瘤患者374例；统计感染率、感染部位分布；采用χ2检验分析患者性别、年龄、肿瘤部位、住院时间、放化疗治疗、基础疾病、使用抗菌药物时间、白细胞数等因素对介入治疗术后发生医院感染是否存在影响；采用Logistic回归分析筛选独立影响因素。结果全组总感染率为16.3%(61/374)；肺癌感染率最高，占35.29%；感染部位以呼吸道为首，占52.46%；年龄、肿瘤部位、住院时间、放化疗、合并症、使用抗菌药、白细胞数是发生感染的危险因素；其中肿瘤部位(OR=8.65，P<0.01)、住院周数(OR=7.23，P<0.01)、放化疗治疗(OR=6.96，P<0.01)、基础疾病(OR=5.26，P<0.01)、使用抗菌药物时间（OR=5.12，P<0.01）是介入治疗后发生感染的高危因素。结论进行介入治疗的肿瘤患者存在多种发生医院感染的不利因素；介入治疗过程中应采用防控感染的措施。
목적：탐토진행개입치료적종류환자의원감염적고위인소。방법선택2010년1월지2012년12월개입치료종류환자374례；통계감염솔、감염부위분포；채용χ2검험분석환자성별、년령、종류부위、주원시간、방화료치료、기출질병、사용항균약물시간、백세포수등인소대개입치료술후발생의원감염시부존재영향；채용Logistic회귀분석사선독립영향인소。결과전조총감염솔위16.3%(61/374)；폐암감염솔최고，점35.29%；감염부위이호흡도위수，점52.46%；년령、종류부위、주원시간、방화료、합병증、사용항균약、백세포수시발생감염적위험인소；기중종류부위(OR=8.65，P<0.01)、주원주수(OR=7.23，P<0.01)、방화료치료(OR=6.96，P<0.01)、기출질병(OR=5.26，P<0.01)、사용항균약물시간（OR=5.12，P<0.01）시개입치료후발생감염적고위인소。결론진행개입치료적종류환자존재다충발생의원감염적불리인소；개입치료과정중응채용방공감염적조시。
Objective To investigate the risk factors of nosocomial infections in tumor patients underwent tu-mor interventional therapy. Methods A total of 374 patients who underwent tumor interventional therapy from Janu-ary 2010 to December 2012 were enrolled in this study. Infection rate and infection location distribution in these pa-tients were statistically analyzed. By using chi-square test, gender, age, tumor location, duration of hospitalization, ra-diotherapy and chemotherapy, number of underlying diseases, and leukocytes count of these patients were analyzed to decide whether these factors are the impact factors of nosocomial infections after tumor interventional therapy. Logis-tic regression was employed to screen independent impact factor. Results The over all infection rate of these patients was 16.3%(61/374), among which the lung cancer incidence was the highest one (35.29%). Meanwhile, respiratory was the most frequent infected location (52.46%). Age, tumor location, duration of hospitalization, radiotherapy and chemotherapy, number of complications, use of antimicrobial drugs, and leukocytes count were the risk factors for nos-ocomial infections, among which the tumor location (OR=8.65, P<0.01), duration of hospitalization (OR=7.23, P<0.01), radiotherapy and chemotherapy (OR=6.96, P<0.01), number of underlying diseases (OR=5.26, P<0.01), and du-ration of use of antimicrobial drugs (OR=5.12, P<0.01) were the high risk factors of nosocomial infections in patients underwent tumor interventional therapy. Conclusion There are a lot of risk factors correlated with nosocomial infec-tions in tumor patients underwent interventional therapy. It is essential to take effective measures to prevent nosocomi-al infections during tumor interventional therapy.