CAJ | 학술논문

目的：对应用榄香烯注射液与放疗方式联合对患有肺癌脑转移的患者实施治疗的临床效果进行研究。方法将我院收治的86例患有肺癌脑转移的患者随机分为对照组和治疗组，平均每组43例。采用常规放疗方式对对照组患者实施治疗；采用榄香烯注射液与放疗方式联合对治疗组患者实施治疗。结果治疗组患者肺癌脑转移病情控制效果明显优于对照组；治疗后半年、一年、三年内存活率明显高于对照组；出现不良反应的人数明显少于对照组；治疗前后血清MMP-2和MMP-9水平的改善幅度明显大于对照组；放疗计划实施时间和住院接受治疗总时间明显短于对照组。结论应用榄香烯注射液与放疗方式联合对患有肺癌脑转移的患者实施治疗的临床效果非常明显。
목적：대응용람향희주사액여방료방식연합대환유폐암뇌전이적환자실시치료적림상효과진행연구。방법장아원수치적86례환유폐암뇌전이적환자수궤분위대조조화치료조，평균매조43례。채용상규방료방식대대조조환자실시치료；채용람향희주사액여방료방식연합대치료조환자실시치료。결과치료조환자폐암뇌전이병정공제효과명현우우대조조；치료후반년、일년、삼년내존활솔명현고우대조조；출현불량반응적인수명현소우대조조；치료전후혈청MMP-2화MMP-9수평적개선폭도명현대우대조조；방료계화실시시간화주원접수치료총시간명현단우대조조。결론응용람향희주사액여방료방식연합대환유폐암뇌전이적환자실시치료적림상효과비상명현。
Objective To study the clinical effects on patients with brain metastases from lung cancer combined with Elemene Injection and radiotherapy. Method 86 patients with brain metastases from lung cancer were randomly divided into control group and treatment group, 43 cases in each group. Control group was given conventional radiotherapy treatment, while treatment group combined Elemene Injection with radiotherapy. Results Compared with control group, treatment group’s disease control effect was obviously better. Survival rates after treatment for six months, one year, three years were higher than control group, and the number of adverse reactions were lower. Serum MMP-2 and MMP-9 levels were significantly greater. Radiotherapy plan time and total time in hospital for treatment were significantly shorter. Conclusion The combination of Elemene Injection with radiotherapy treatment for patients with brain metastases from lung cancer is very obvious.