CAJ | 학술논문

目的：探讨莲芪胶囊在中晚期原发性肝癌治疗中的临床效果及应用价值。方法选择在四川省广安市广安区中医院治疗的中晚期原发性肝癌患者168例，随机分为观察组和对照组，2组均采用相同的化疗方案，对照组辅助使用消癌平片进行治疗，观察组辅助使用莲芪胶囊进行治疗，观察2组的临床治疗效果及安全性。结果观察组临床治疗总有效率与对照组总有效率比较差异无统计学意义。观察组生活质量改善率与对照组生活质量改善率比较差异有统计学意义（P＜0.05）。观察组发生不良反应发生率与对照组发生不良反应发生率比较经统计学分析，差异有统计学意义（P＜0.05）。结论莲芪胶囊联合化疗方案应用于中晚期原发性肝癌患者的全程治疗能够有效改善患者生活质量，控制肿瘤的生长，对患者化疗起到增效减毒的作用，值得在临床上推广使用。
목적：탐토련기효낭재중만기원발성간암치료중적림상효과급응용개치。방법선택재사천성엄안시엄안구중의원치료적중만기원발성간암환자168례，수궤분위관찰조화대조조，2조균채용상동적화료방안，대조조보조사용소암평편진행치료，관찰조보조사용련기효낭진행치료，관찰2조적림상치료효과급안전성。결과관찰조림상치료총유효솔여대조조총유효솔비교차이무통계학의의。관찰조생활질량개선솔여대조조생활질량개선솔비교차이유통계학의의（P＜0.05）。관찰조발생불량반응발생솔여대조조발생불량반응발생솔비교경통계학분석，차이유통계학의의（P＜0.05）。결론련기효낭연합화료방안응용우중만기원발성간암환자적전정치료능구유효개선환자생활질량，공제종류적생장，대환자화료기도증효감독적작용，치득재림상상추엄사용。
Objective To discuss clinical effect and clinical application value of lianqi capsules treated with the middle-late stage primary liver cancer. Method We choosed 168 cases of middle-late stage primary liver cancer patients in Guang'an District Hospital,Sichuan province,Guang'an treatment, and they were randomly divided into observation group and control group. Both two groups were treated with the same chemotherapy regimens. Pingxiaopian were auxiliarily used in control group, and lianqi capsules in observation group. Clinical curative effect and security of two groups were observed. Result There was no statistically significant difference between the total effective rate of clinical treatment group and control group. There were statistically significant differences between two groups on the quality of life period (P<0.05) and adverse reactions (P<0.05). Conclusion Lianqi capsules combined with chemotherapy was used in treatment of patients with locally advanced primary liver cancer, and it can effectively improve the patients’quality of life in the whole process, control the growth of the tumor, and increased synergistic effect of chemotherapy for patients. So Lianqi capsules was worthy in clinical application and popularization.