江西中医学院学报
江西中醫學院學報
강서중의학원학보
JOURNAL OF JIANGXI COLLEGE OF TRADITIONAL CHINESE MEDICINE
2014年
2期
55-57,58
,共4页
香芍疏肝口服液%薄层色谱法%高效液相色谱法%芍药苷%质量标准
香芍疏肝口服液%薄層色譜法%高效液相色譜法%芍藥苷%質量標準
향작소간구복액%박층색보법%고효액상색보법%작약감%질량표준
Xiangshao Shugan Oral Liquid%TLC%HPLC%Paeoniflorin%quality standard
目的：建立香芍疏肝口服液的质量控制标准。方法：采用薄层色谱法对制剂中的香附、白芍和柴胡进行定性鉴别；采用高效液相色谱法对制剂中的芍药苷进行含量测定。结果：薄层色谱法可鉴别出香附、白芍和柴胡，斑点清晰，分离度好，且阴性对照无干扰；芍药苷在0．2308～1．1540μg范围内呈良好线性关系，r＝0．9999，平均回收率为98．05％，RSD＝0．91％。结论：本方法操作简便易行、准确可靠、灵敏度高、重现性好，可作为香芍疏肝口服液的质量控制方法。
目的：建立香芍疏肝口服液的質量控製標準。方法：採用薄層色譜法對製劑中的香附、白芍和柴鬍進行定性鑒彆；採用高效液相色譜法對製劑中的芍藥苷進行含量測定。結果：薄層色譜法可鑒彆齣香附、白芍和柴鬍，斑點清晰，分離度好，且陰性對照無榦擾；芍藥苷在0．2308～1．1540μg範圍內呈良好線性關繫，r＝0．9999，平均迴收率為98．05％，RSD＝0．91％。結論：本方法操作簡便易行、準確可靠、靈敏度高、重現性好，可作為香芍疏肝口服液的質量控製方法。
목적：건립향작소간구복액적질량공제표준。방법：채용박층색보법대제제중적향부、백작화시호진행정성감별；채용고효액상색보법대제제중적작약감진행함량측정。결과：박층색보법가감별출향부、백작화시호，반점청석，분리도호，차음성대조무간우；작약감재0．2308～1．1540μg범위내정량호선성관계，r＝0．9999，평균회수솔위98．05％，RSD＝0．91％。결론：본방법조작간편역행、준학가고、령민도고、중현성호，가작위향작소간구복액적질량공제방법。
Objective:To establish the quality standard of Xiangshao Shugan Oral Liquid .Methods: Rhizoma Cyperi , Radix Paeoniae Alba and Radix Bupleuri in Xiangshao Shugan Oral Liquid were identified by TLC .The content of Paeoniflorin was determined by HPLC.Results:The TLC spots of Rhizoma Cyperi , Radix Paeoniae Alba and Radix Bupleuri were clear with good separation and free of interference of negative samples .The linear ranges of Paeoniflorin was 0.2308~1.1540μg, the average recovery rate was 98.05%, RSD=0.91%.Conclusion:The method is simple, accurate, sensitive and reliable, which can be used to control the quality of Xiang-shao Shugan Oral Liquid .
