CAJ | 학술논문

目的：口服INH预防HIV的结核机会性感染引发的类郝氏反应。并揭示INH对HIV的TB性机会感染的防治作用。方法：对口服INH防治HIV并发TB机会感染的国家项目，用药过程中，出现的类郝氏反应。采用回顾分析法进行总结报道。结果：治疗组626例，出现的发热，胃肠道状况，但较复方抗痨药发现早、病状轻。及咳、喘、心慌、胸闷，且X线示有活动性炎性病灶（共发现16例），发生率为26％，而对照组9（服用安慰剂）无此反应病例（P﹤0．01）。结论：口服INH亦可引发类郝氏反应，应引起临床医生的注意。治疗方法用激素与对症治疗。
목적：구복INH예방HIV적결핵궤회성감염인발적류학씨반응。병게시INH대HIV적TB성궤회감염적방치작용。방법：대구복INH방치HIV병발TB궤회감염적국가항목，용약과정중，출현적류학씨반응。채용회고분석법진행총결보도。결과：치료조626례，출현적발열，위장도상황，단교복방항로약발현조、병상경。급해、천、심황、흉민，차X선시유활동성염성병조（공발현16례），발생솔위26％，이대조조9（복용안위제）무차반응병례（P﹤0．01）。결론：구복INH역가인발류학씨반응，응인기림상의생적주의。치료방법용격소여대증치료。
Objective :to know the class oral INH trigger Hao Shi reaction .Reveal INH TB of opportunistic infections of the HIV prevention role . Methods :the oral INH national project of prevention and treatment of HIV and TB opportunistic infections ,in the process of drug class Hao Shi re-action .Using retrospective analysis to summary report .Results:the treatment group 626 examples ,the fever ,gastrointestinal tract ,but is com-pound the chemotherapy drug discovery ,light conditions .And cough ,asthma ,flustered ,chest tightness ,and X-ray shows have active inflammato-ry lesions (16 cases) found ,rate of 26% ,while the control group (placebo) of 9 cases had no reaction (P﹤0 .01) .Conclusion :oral INH can also lead to class Hao Shi reaction ,should attract the attention of clinicians .Treatment with hormone and symptomatic treatment .