CAJ | 학술논문

目的：探讨新生儿乙肝疫苗接种以后的免疫效果。方法：选取2009年1月～2009年12月在我院接受乙肝疫苗接种的147例新生儿的临床资料进行分析，观察新生儿在anti-HBs阳转率以及免疫水平。结果：在被检测的147例的儿童中，2岁时被检测出anti-HBs阳性的有132例，阳性率达到89．80％，阴性的则有15例，阴性率为10．20％。在其3岁时被检测出anti-HBs阳性的有112例，阳性率为76．19％，阴性的有35例，阴性率为23．81％。对147例儿童2岁和3岁检测的结果进行对比，存在统计学意义，P＜0．05。在对这些儿童连续3年进行的随访中发现，最终147例儿童的HBsAg都显示阴性，并没有发现乙肝病毒携带者。结论：乙肝疫苗接种能够有效减少乙肝病毒携带者，在乙肝疫苗的防治工作上具有一定的积极意义。
목적：탐토신생인을간역묘접충이후적면역효과。방법：선취2009년1월～2009년12월재아원접수을간역묘접충적147례신생인적림상자료진행분석，관찰신생인재anti-HBs양전솔이급면역수평。결과：재피검측적147례적인동중，2세시피검측출anti-HBs양성적유132례，양성솔체도89．80％，음성적칙유15례，음성솔위10．20％。재기3세시피검측출anti-HBs양성적유112례，양성솔위76．19％，음성적유35례，음성솔위23．81％。대147례인동2세화3세검측적결과진행대비，존재통계학의의，P＜0．05。재대저사인동련속3년진행적수방중발현，최종147례인동적HBsAg도현시음성，병몰유발현을간병독휴대자。결론：을간역묘접충능구유효감소을간병독휴대자，재을간역묘적방치공작상구유일정적적겁의의。
Purpose:Discussion after neonatal hepatitis B vaccination immune effect .Method:Select January 2009-December 2009 clinical data in our hospital 147 cases of hepatitis B vaccinartion of newborns were analyzed to observe the newborn in anti -HBs seroconversion rates and immunity levels .Result :In 147 cases of children being tested ,the age of 2 were detected positive for anti -HBs 132 cases ,the positive rate was 89 .80% ,compared with 15 cases negative ,negative rate of 10 .20% .In its three years of age were detected positive for anti -HBs 112 cases ,the positive rate was 76 .19% ,negative in 35 cases ,negative rate of chil-dren 2 years old and 3-year-old comparative testing ,there were statistically significant ,P<0 .05 .In the follow -up of these children three consecutive years of discovery ,HBaAg final 147 cases of children have shown negative ,and did not find the hepatitis B virus carriers .Conclusion:Hepatitis B vaccine can be effective in reducing hepatitis B virus carriers ,has certain positive significanve of hepatitis B vaccine in prevention work .