中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
10期
44-44,45
,共2页
麻龙安神胶囊%芍药苷%高效液相色谱法
痳龍安神膠囊%芍藥苷%高效液相色譜法
마룡안신효낭%작약감%고효액상색보법
Malong Anshen Capsules%paeoniflorin%HPLC
目的:建立测定麻龙安神胶囊中芍药苷含量的高效液相色谱法。方法色谱柱为ODS-C18柱(250 mm ×4.6 mm,5μm),流动相为乙腈-0.1%磷酸(14:86),流速1.0 mL/min,检测波长230 nm。结果芍药苷进样量在0.1448~1.4775μg范围内与峰面积线性关系良好( r=0.9999),平均加样回收率为99.56%,RSD=0.41%( n=9)。结论该方法简便快速、结果准确,可较好地控制该制剂质量。
目的:建立測定痳龍安神膠囊中芍藥苷含量的高效液相色譜法。方法色譜柱為ODS-C18柱(250 mm ×4.6 mm,5μm),流動相為乙腈-0.1%燐痠(14:86),流速1.0 mL/min,檢測波長230 nm。結果芍藥苷進樣量在0.1448~1.4775μg範圍內與峰麵積線性關繫良好( r=0.9999),平均加樣迴收率為99.56%,RSD=0.41%( n=9)。結論該方法簡便快速、結果準確,可較好地控製該製劑質量。
목적:건립측정마룡안신효낭중작약감함량적고효액상색보법。방법색보주위ODS-C18주(250 mm ×4.6 mm,5μm),류동상위을정-0.1%린산(14:86),류속1.0 mL/min,검측파장230 nm。결과작약감진양량재0.1448~1.4775μg범위내여봉면적선성관계량호( r=0.9999),평균가양회수솔위99.56%,RSD=0.41%( n=9)。결론해방법간편쾌속、결과준학,가교호지공제해제제질량。
Objective To establish a HPLC method for the content determination of paeoniflorin in Malong Anshen Capsule. Methods The chromatographic column ODS C18(250 mm × 4. 6 mm,5 μm)was adopted withacetonitrile-0. 1% phosphoric acid(14:86)as the mobile phase. The paeoniflorin content was detected at the wavelength of 230 nm and the flow rate was 1. 0 mL/min. Results The sample size of paeoniflorin in the range of 0. 144 8-1. 447 5 μg had a good linear relationship with the peak area( r=0. 999 9), the average recovery rate was 99. 56%,RSD=0. 41%( n=9). Conclusion The established method is simple,rapid and accurate in the detection results and can better control the quality of this preparation.