临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
2014年
11期
902-904
,共3页
过敏性紫癜性肾炎%中西医结合%临床疗效
過敏性紫癜性腎炎%中西醫結閤%臨床療效
과민성자전성신염%중서의결합%림상료효
Henoch-schonleinpurpuranephritis(HSPN)%Integratedtraditionalandwesternmedicine%Clinicaleffects
目的：探讨中西医结合治疗紫癜性肾炎的方法及临床疗效。方法选取92例紫癜性肾炎患者为研究对象，随机分为两组，其中对照组40例采用单纯西药治疗；观察组52例在西药治疗基础上，予加减清营汤治疗。观察分析两组患者治疗6个月后的临床疗效及实验室检查指标改善情况。结果观察组的治疗总有效率（92.3%）优于对照组（75.0%），差异有统计学意义（χ2=5.249，P <0.05）。观察组患者不良反应发生率（15.4%）低于对照组（17.5%），差异有统计学意义（χ2=7.414，P <0.05）。两组患者治疗后尿红细胞、24 h尿蛋白、血肌酐有改善，且观察组改善更明显，差异有统计学意义（ P <0.05）。结论中西医结合治疗紫癜性肾炎，能有效改善临床指标和症状，降低不良反应发生率，具有较好的临床疗效。
目的：探討中西醫結閤治療紫癜性腎炎的方法及臨床療效。方法選取92例紫癜性腎炎患者為研究對象，隨機分為兩組，其中對照組40例採用單純西藥治療；觀察組52例在西藥治療基礎上，予加減清營湯治療。觀察分析兩組患者治療6箇月後的臨床療效及實驗室檢查指標改善情況。結果觀察組的治療總有效率（92.3%）優于對照組（75.0%），差異有統計學意義（χ2=5.249，P <0.05）。觀察組患者不良反應髮生率（15.4%）低于對照組（17.5%），差異有統計學意義（χ2=7.414，P <0.05）。兩組患者治療後尿紅細胞、24 h尿蛋白、血肌酐有改善，且觀察組改善更明顯，差異有統計學意義（ P <0.05）。結論中西醫結閤治療紫癜性腎炎，能有效改善臨床指標和癥狀，降低不良反應髮生率，具有較好的臨床療效。
목적：탐토중서의결합치료자전성신염적방법급림상료효。방법선취92례자전성신염환자위연구대상，수궤분위량조，기중대조조40례채용단순서약치료；관찰조52례재서약치료기출상，여가감청영탕치료。관찰분석량조환자치료6개월후적림상료효급실험실검사지표개선정황。결과관찰조적치료총유효솔（92.3%）우우대조조（75.0%），차이유통계학의의（χ2=5.249，P <0.05）。관찰조환자불량반응발생솔（15.4%）저우대조조（17.5%），차이유통계학의의（χ2=7.414，P <0.05）。량조환자치료후뇨홍세포、24 h뇨단백、혈기항유개선，차관찰조개선경명현，차이유통계학의의（ P <0.05）。결론중서의결합치료자전성신염，능유효개선림상지표화증상，강저불량반응발생솔，구유교호적림상료효。
Objective Tostudyclinicaleffectsofintegratedtraditionalandwesternmedicineinthetreatmentofhenoch-schonleinpur-puranephritis(HSPN).Methods 92casesofpatientsdiagnosedwithadultpurpuranephritiswereincludedintothisstudyandwererandomly divided into two groups. Patients in the control group(40 cases)were given western medicine treatment,po administered with prednisone. The a-mount of prednisone was reduced eight weeks later,and the reduction rate was 0. 1 mg/kg per week,and finally 5 mg/d maintained the therapy. The patients of observation group(52 cases)were given traditional medicine Qingying Soup on the basis of control group. The treatment lasted for six months. After the treatment,the clinical efficacy and adverse reactions of the two groups were compared. The erythrocyturia,24 h urinary pro-teinandserumcreatininewerecompared.Results Thetotaleffectiveratewas92.3%inobservationgroupand75.0%incontrolgroup.There was a significant difference between the two groups(χ2 =5. 249,P <0. 05). The adverse reactions rate of the two groups was statistical difference between them(χ2 =7. 414,P <0. 05). And the test results of the erythrocyturia,24 h urinary protein and serum creatinine were statistical signif-icancebetweenthetwogroups.Conclusion Combinedtherapyofintegratedtraditionalandwesternmedicinecansignificantlyimprovetheclinical symptoms. This method had less adverse reactions,has good effects and worthy of clinical promotion.
