CAJ | 학술논문

目的：通过对危、重型手足口病患儿血液中的肾上腺素及去甲肾上腺素含量的测定，探讨手足口病病情由重型向危重型进展的预警指标，以期对危重症手足口病患儿进行早期识别、早期干预，以降低其病死率。方法：根据病情将患儿分为重症组和危重症组，在2组患儿于安静状态下，抽取静脉血，应用荧光检测的方法测肾血清中上腺素、去甲肾上腺素水平。结果：肾上腺素水平：重型组1．48±0．58、危重型组2．08±0．1．72，经t检验，P＞0．05差异无统计学意义。去甲肾上腺素水平：重型组1．58±0．68、危重型组2．28±1．02，经t检验，P＞0．05差异无统计学意义。结论：血清肾上腺素及去甲肾上腺素水平均不能作为早期发现手足口病由重型向危重型进展的预警指标。
목적：통과대위、중형수족구병환인혈액중적신상선소급거갑신상선소함량적측정，탐토수족구병병정유중형향위중형진전적예경지표，이기대위중증수족구병환인진행조기식별、조기간예，이강저기병사솔。방법：근거병정장환인분위중증조화위중증조，재2조환인우안정상태하，추취정맥혈，응용형광검측적방법측신혈청중상선소、거갑신상선소수평。결과：신상선소수평：중형조1．48±0．58、위중형조2．08±0．1．72，경t검험，P＞0．05차이무통계학의의。거갑신상선소수평：중형조1．58±0．68、위중형조2．28±1．02，경t검험，P＞0．05차이무통계학의의。결론：혈청신상선소급거갑신상선소수평균불능작위조기발현수족구병유중형향위중형진전적예경지표。
Objective:To discuss the early warning indicator from severe to critical hand -foot-mouth disease through detecting the serum levels of adrenaline and noradrenaline of the two groups children , to recognize and interfere the critical , to reduce the mortality rate.Methods:We divided the children to sever group and critical group based on the conditions .We extracted the venous blood when the children in resting state ,detected the serum levels of adrenaline and noradrenaline using the fluorescence detection .Results:The level of adrenaline:the sever group (1.48 ±0.58), the critical group (2.08 ±0.1.72), the data had no statistical significance using t -test;the level of noradrenaline:the severe group (1.58 ±0.68), the critical group(2.28 ±1.02), they had no statistical significance using t-test.Conclusion:The serum levels of adrenaline and noradrenaline were not the early warning indicators from the severe to critical hand-foot-mouth disease .