医药工程设计
醫藥工程設計
의약공정설계
PHARMACEUTICAL ENGINEERING DESIGN
2014年
2期
44-46,57
,共4页
严小生%邵洪根%李强
嚴小生%邵洪根%李彊
엄소생%소홍근%리강
结晶%搅拌器%计算流体力学%速度分布均匀性%晶体体积含量分布均匀性
結晶%攪拌器%計算流體力學%速度分佈均勻性%晶體體積含量分佈均勻性
결정%교반기%계산류체역학%속도분포균균성%정체체적함량분포균균성
crystallization%agitator%computational fluid dynamics%velocity distribution homogeneity%crystal volume distribution homogeneity
采用计算流体力学（CFD）方法对啶虫脒结晶釜进行了模拟与优化，考察了不同搅拌转速下的速度分布均匀性和晶体体积含量分布均匀性，结果表明高效轴流型桨SP306对晶体悬浮的效果较好，搅拌转速对晶体体积含量分布均匀性有显著影响，确定了90 r/min为优化后的搅拌转速。经工业应用，验证了优化设计的合理性，产品粒径分布有明显改善。
採用計算流體力學（CFD）方法對啶蟲脒結晶釜進行瞭模擬與優化，攷察瞭不同攪拌轉速下的速度分佈均勻性和晶體體積含量分佈均勻性，結果錶明高效軸流型槳SP306對晶體懸浮的效果較好，攪拌轉速對晶體體積含量分佈均勻性有顯著影響，確定瞭90 r/min為優化後的攪拌轉速。經工業應用，驗證瞭優化設計的閤理性，產品粒徑分佈有明顯改善。
채용계산류체역학（CFD）방법대정충미결정부진행료모의여우화，고찰료불동교반전속하적속도분포균균성화정체체적함량분포균균성，결과표명고효축류형장SP306대정체현부적효과교호，교반전속대정체체적함량분포균균성유현저영향，학정료90 r/min위우화후적교반전속。경공업응용，험증료우화설계적합이성，산품립경분포유명현개선。
By using computational lfuid dynamics (CFD), the design of acetamiprid crystallizing kettle was simulated and optimized. The distribution homogeneities of velocity and crystal volume in the vessel were investigated with different rotating speeds. It has been shown that use of impeller SP306 with axial lfow type has better effect for crystal suspension and rotating speed has remarkable inlfuence to crystal volume distribution homogeneity. The optimum rotating speed has been determined as 90 r/min. Through the application in industry, this optimum design has been proved appropriate that product size distribution was obviously improved.
