中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
14期
86-86,89
,共2页
喜炎平%西咪替丁%利巴韦林%手足口病
喜炎平%西咪替丁%利巴韋林%手足口病
희염평%서미체정%리파위림%수족구병
Xiyanping%Cimetidine%Ribavirin%Hand foot and mouth disease
目的：探讨喜炎平联合西咪替丁治疗儿童手足口病的临床疗效。方法：2013年1月-2014年1月收治手足口病患儿120例，随机分成观察组和对照组，各60例。对照组给予喜炎平0.2～0.4ml/kg肌注，1次/日，利巴韦林加入10～15mg/(kg·日)5%GS 静滴；观察组在对照组的基础上加西咪替丁0.2～0.4mg/(kg·日)静滴，两组治疗5天。结果：观察组口腔症状缓解时间(1.74±0.51)天，皮疹好转时间(3.1±1.2)天；对照组口腔症状缓解时间(3.3±1.4)天，皮疹好转时间(4.8±1.6)天，两组比较差异有统计学意义(P＜0.05)。观察组显效37例(61.7%)，有效21例(35.0%)，无效2例，总有效率96.7%；对照组显效28例(46.7%)，有效22例(36.7%)，无效10例，总有效率83.3%，两组比较差异有统计学意义(P＜0.05)。结论：喜炎平联合西咪替丁治疗儿童手足口病症状缓解快，疗效显著，值得推广。
目的：探討喜炎平聯閤西咪替丁治療兒童手足口病的臨床療效。方法：2013年1月-2014年1月收治手足口病患兒120例，隨機分成觀察組和對照組，各60例。對照組給予喜炎平0.2～0.4ml/kg肌註，1次/日，利巴韋林加入10～15mg/(kg·日)5%GS 靜滴；觀察組在對照組的基礎上加西咪替丁0.2～0.4mg/(kg·日)靜滴，兩組治療5天。結果：觀察組口腔癥狀緩解時間(1.74±0.51)天，皮疹好轉時間(3.1±1.2)天；對照組口腔癥狀緩解時間(3.3±1.4)天，皮疹好轉時間(4.8±1.6)天，兩組比較差異有統計學意義(P＜0.05)。觀察組顯效37例(61.7%)，有效21例(35.0%)，無效2例，總有效率96.7%；對照組顯效28例(46.7%)，有效22例(36.7%)，無效10例，總有效率83.3%，兩組比較差異有統計學意義(P＜0.05)。結論：喜炎平聯閤西咪替丁治療兒童手足口病癥狀緩解快，療效顯著，值得推廣。
목적：탐토희염평연합서미체정치료인동수족구병적림상료효。방법：2013년1월-2014년1월수치수족구병환인120례，수궤분성관찰조화대조조，각60례。대조조급여희염평0.2～0.4ml/kg기주，1차/일，리파위림가입10～15mg/(kg·일)5%GS 정적；관찰조재대조조적기출상가서미체정0.2～0.4mg/(kg·일)정적，량조치료5천。결과：관찰조구강증상완해시간(1.74±0.51)천，피진호전시간(3.1±1.2)천；대조조구강증상완해시간(3.3±1.4)천，피진호전시간(4.8±1.6)천，량조비교차이유통계학의의(P＜0.05)。관찰조현효37례(61.7%)，유효21례(35.0%)，무효2례，총유효솔96.7%；대조조현효28례(46.7%)，유효22례(36.7%)，무효10례，총유효솔83.3%，량조비교차이유통계학의의(P＜0.05)。결론：희염평연합서미체정치료인동수족구병증상완해쾌，료효현저，치득추엄。
Objective:To explore the curative effect of Xiyanping combined with cimetidine in the treatment of children with hand foot and mouth disease.Methods:120 cases of hand foot and mouth disease were admitted and were randomly divided into the con-trol group and the observation group.The control group were given Xiyanping injection of 0.2 to 0.4ml/kg,1 time/day,ribavirin joined in 10 to 15mg/(kg·day)5% GS for intravenous drip.The observation group added cimetidine 0.2 to 0.4mg/(kg·day)for intra-venous drip on the basis of the control group.The treatment time of two groups was 5 days.Results:In the observation group,the re-mission time of oral symptoms was 1.74±0.51 days,and the turnaround time of rash was 3.1±1.2 days.In the control group,the re-mission time of oral symptoms was 3.3±1.4 days,and the turnaround time of rash was 4.8±1.6 days.There are statistically signifi-cant differences between two groups(P<0.05).In the observation group,37 cases(61.7%) were markedly effective, 21 cases(35%) were effective,2 cases were ineffective,and the total efficiency was 96.7%.In the control group,28 cases(46.7%) were markedly ef-fective,22 cases(36.7%) were effective,10 cases were ineffective,and the total efficiency was 83.3%.There are statistically signifi-cant differences between two groups(P<0.05).Conclusion:The curative effect of Xiyanping combined with cimetidine in the treat-ment of children with hand foot and mouth disease is significant, and symptom relief is fast,so it is worthy of promotion.
