CAJ | 학술논문

目的：观察他汀类药物在冠心病治疗中的作用。方法：2010年1月-2012年12月收治冠心病患者96例，随机分为常规治疗组和他汀类药物治疗组，各48例。对两组患者治疗前后的血脂水平及心血管不良事件的发生率进行统计分析。结果：两组患者的血脂在治疗后均较治疗前下降，但他汀药物治疗组血脂下降程度明显高于常规治疗组，差异有统计学意义。他汀类药物治疗组的心血管不良事件的发生率也明显低于常规治疗组，并且他汀类药物的不良反应较小。结论：对冠心病患者进行他汀类药物调脂治疗，可以有效稳定冠脉粥样斑块，减少心血管不良事件的发生率，改善患者的生存质量。
목적：관찰타정류약물재관심병치료중적작용。방법：2010년1월-2012년12월수치관심병환자96례，수궤분위상규치료조화타정류약물치료조，각48례。대량조환자치료전후적혈지수평급심혈관불량사건적발생솔진행통계분석。결과：량조환자적혈지재치료후균교치료전하강，단타정약물치료조혈지하강정도명현고우상규치료조，차이유통계학의의。타정류약물치료조적심혈관불량사건적발생솔야명현저우상규치료조，병차타정류약물적불량반응교소。결론：대관심병환자진행타정류약물조지치료，가이유효은정관맥죽양반괴，감소심혈관불량사건적발생솔，개선환자적생존질량。
Objective:To observe the effect of statins in the treatment of coronary heart disease.Methods:We selected 96 cases of coronary heart disease patients from January 2010 to December 2012.These patients were randomly divided into routine treatment group and the statin treatment group with 48 cases in each.Lipid levels and the incidence of adverse cardiovascular events before and after treatment of the two groups were analyzed.Results:Blood lipid after treatment were decreased than before treatment of the two groups,but the decline of blood lipid of statin treatment group was significantly higher than normal group.The difference had statistical significance.The incidence of adverse cardiovascular events of statin treatment group was significantly lower than the conventional treatment group,and the adverse reactions of statin treatment group was small.Conclusion:The application of statins in the treatment of coronary heart disease,can effectively stabilize coronary atherosclerotic plaque,reduce the incidence of adverse cardiovascular events,and improve the quality of life of patients.