CAJ | 학술논문

目的：分析颈动脉狭窄程度与认知功能MMSE评分的关系。方法：回顾性分析本院2010-2012年收治的122例门诊及住院颈动脉狭窄患者的全部资料，所有患者行颈动脉多普勒超声检查后，按颈动脉狭窄程度分为三组，并行认知功能MMSE评分，研究动脉狭窄程度与认知功能MMSE评分的关系。结果：81例颈内动脉患者中，发生左侧的有38例（31.1%），右侧的有22例（18.0%），双侧的有21例（17.2%）；13例颈外动脉患者中，发生左侧的有6例（4.9%），右侧的有3例（2.5%），双侧的有4例（3.3%）；28例颈总动脉患者中，发生左侧的有15例（12.3%），右侧的有6例（4.9%），双侧的有7例（5.7%），结果有统计学差异（P<0.05）；Ⅰ组的MMSE评分为（28.8±1.5）分，Ⅱ组为（28.2±1.4）分，Ⅲ组为（27.3±1.1）分，三组比较差异有统计学意义（P<0.05）；且随着颈动脉狭窄程度的加重，MMSE评分降低，两者呈正相关（r=0.731，P<0.05）结论：颈动脉狭窄程度与认知功能MMSE评分呈正相关，颈动脉狭窄超过75%的患者应行颈动脉内膜剥脱术或颈动脉内支架成形术治疗。
목적：분석경동맥협착정도여인지공능MMSE평분적관계。방법：회고성분석본원2010-2012년수치적122례문진급주원경동맥협착환자적전부자료，소유환자행경동맥다보륵초성검사후，안경동맥협착정도분위삼조，병행인지공능MMSE평분，연구동맥협착정도여인지공능MMSE평분적관계。결과：81례경내동맥환자중，발생좌측적유38례（31.1%），우측적유22례（18.0%），쌍측적유21례（17.2%）；13례경외동맥환자중，발생좌측적유6례（4.9%），우측적유3례（2.5%），쌍측적유4례（3.3%）；28례경총동맥환자중，발생좌측적유15례（12.3%），우측적유6례（4.9%），쌍측적유7례（5.7%），결과유통계학차이（P<0.05）；Ⅰ조적MMSE평분위（28.8±1.5）분，Ⅱ조위（28.2±1.4）분，Ⅲ조위（27.3±1.1）분，삼조비교차이유통계학의의（P<0.05）；차수착경동맥협착정도적가중，MMSE평분강저，량자정정상관（r=0.731，P<0.05）결론：경동맥협착정도여인지공능MMSE평분정정상관，경동맥협착초과75%적환자응행경동맥내막박탈술혹경동맥내지가성형술치료。
Objective:To analyze the relationship of degree of CAS with MMSE score of cognitive function. Method:Data of 122 patients with CAS from inpatient department and outpatient department were retrospectively analyzed. All patients were given carotid artery Doppler ultrasound examinations and were divided into three groups according to the degree of carotid stenosis,then evaluated by MMSE scores of cognitive function. Relationship of degree of CAS with MMSE score of cognitive function was studied. Result:Among 81 patients of internal carotid artery,there were left side 38 cases(31.1%),right side 22 cases(18.0%),both sides 21 cases(17.2%);among 13 patients of external carotid artery,there were left side 6 cases(4.9%),right side 3 cases(2.5%),both sides 4 cases(3.3%);among 28 patients of common carotid artery,there were left side 15 cases(12.3%),right side 6 cases(4.9%),both sides 7 cases (5.7%). MMSE score of the group Ⅰwas(28.8±1.5),MMSE score of the group Ⅱwas(28.2±1.4),MMSE score of the groupⅢwas(27.3±1.1),the difference was statistically significant between the three groups(P<0.05);This implied that the severer the degree of CAS was,the lower the MMSE score was,both were positively correlated(r=0.731, P<0.05). Conclusion:Degree of CAS has a positive relationship with MMSE score of cognitive function. Patients with CAS>75%should have carotid endarterectomy or carotid stent angioplasty for treatment.