当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
17期
64-65
,共2页
氟康唑%复发性假丝酵母菌性阴道炎%临床效果
氟康唑%複髮性假絲酵母菌性陰道炎%臨床效果
불강서%복발성가사효모균성음도염%림상효과
Fluconazole%Recurrent vulvovaginal candidiasis%Clinical effect
目的：为了探讨临床有效治疗复发性假丝酵母菌性阴道炎的方法，从而为复发性假丝酵母菌性阴道炎的临床相关研究提供科学依据。方法本研究选取了香港大学深圳医院2009年1月～2012年9月期间收治的复发性假丝酵母菌性阴道炎患者172例为研究对象，随机将患者分成2组，分别为对照组和观察组（n=86），对照组给予患者制菌霉素，观察组给予氟康唑治疗。观察比较2组患者实施不同治疗方法半年后的临床治疗效果，以及停药后半年内的复发情况。结果对照组86例患者中治愈78例，治愈率为90.70%；观察组86例患者中治愈85例，治愈率为98.84%，治愈率组间比较观察组患者显著的高于对照组患者，且差异具有统计学意义（χ2=5.7451，P=0.0165）；复发率组间比较，观察组患者的情况明显优于对照组，且差异具有统计学意义（χ2=4.9765，P=0.0257）。结论在临床针对复发性假丝酵母菌性阴道炎患者实施治疗的实践过程中，采用氟康唑实施治疗的临床优势明显，是临床治疗复发性假丝酵母菌性阴道炎的安全可靠选择。
目的：為瞭探討臨床有效治療複髮性假絲酵母菌性陰道炎的方法，從而為複髮性假絲酵母菌性陰道炎的臨床相關研究提供科學依據。方法本研究選取瞭香港大學深圳醫院2009年1月～2012年9月期間收治的複髮性假絲酵母菌性陰道炎患者172例為研究對象，隨機將患者分成2組，分彆為對照組和觀察組（n=86），對照組給予患者製菌黴素，觀察組給予氟康唑治療。觀察比較2組患者實施不同治療方法半年後的臨床治療效果，以及停藥後半年內的複髮情況。結果對照組86例患者中治愈78例，治愈率為90.70%；觀察組86例患者中治愈85例，治愈率為98.84%，治愈率組間比較觀察組患者顯著的高于對照組患者，且差異具有統計學意義（χ2=5.7451，P=0.0165）；複髮率組間比較，觀察組患者的情況明顯優于對照組，且差異具有統計學意義（χ2=4.9765，P=0.0257）。結論在臨床針對複髮性假絲酵母菌性陰道炎患者實施治療的實踐過程中，採用氟康唑實施治療的臨床優勢明顯，是臨床治療複髮性假絲酵母菌性陰道炎的安全可靠選擇。
목적：위료탐토림상유효치료복발성가사효모균성음도염적방법，종이위복발성가사효모균성음도염적림상상관연구제공과학의거。방법본연구선취료향항대학심수의원2009년1월～2012년9월기간수치적복발성가사효모균성음도염환자172례위연구대상，수궤장환자분성2조，분별위대조조화관찰조（n=86），대조조급여환자제균매소，관찰조급여불강서치료。관찰비교2조환자실시불동치료방법반년후적림상치료효과，이급정약후반년내적복발정황。결과대조조86례환자중치유78례，치유솔위90.70%；관찰조86례환자중치유85례，치유솔위98.84%，치유솔조간비교관찰조환자현저적고우대조조환자，차차이구유통계학의의（χ2=5.7451，P=0.0165）；복발솔조간비교，관찰조환자적정황명현우우대조조，차차이구유통계학의의（χ2=4.9765，P=0.0257）。결론재림상침대복발성가사효모균성음도염환자실시치료적실천과정중，채용불강서실시치료적림상우세명현，시림상치료복발성가사효모균성음도염적안전가고선택。
Objective To explore the clinical effective method for the treatment of recurrent Candida vaginitis, so as to provide the scientific basis for the clinical research of recurrent Candida vaginitis.Methods This study selected Shenzhen Hospital of Hong Kong University from 2009 January to 2012 September, recurrent Candida vaginitis patients 172 patients as the research object, randomly divided into two groups, which were control group and observation group, 86 cases in each group, the control group patients were given nystatin, the observation group givenfluconazole therapy. Clinical observation of the therapeutic effect of two groups were compared after the implementation of half of different treatment methods, and relapse after stopping within half a year.Results In the control group 78 cases were cured in 86 patients, the cure rate was 90.70%; 86 patients in observation group 85 cases were cured, the cure rate was 98.84%, the cure rate between the two groups patients in the observation group were significantly higher than the control group, and the difference was statistically significant (χ2=5.7451,P=0.0165); compare the recurrence rate between group, observation group were significantly better than the control group, and the difference was statistically significant (χ2=4.9765,P=0.0257). Conclusion In clinical practice for recurrent Candida vaginitis were treated in the practice process, with obvious clinical advantage offluconazole therapy, is a safe and reliable choice in the clinical treatment of recurrent Candida vaginiti.
