国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
3期
404-407
,共4页
氯乙醇%环氧乙烷%大口径毛细管柱
氯乙醇%環氧乙烷%大口徑毛細管柱
록을순%배양을완%대구경모세관주
Ethyl chloride%Ethylene oxide%Large caliber capillary column
目的 改进明胶空心胶囊中残留氯乙醇和环氧乙烷的测定方法.方法 采用大口径毛细管柱代替标准方法中规定的10％聚乙二醇填充柱,检测器采用FID和TCD,分别进行测定.结果 对氯乙醇和环氧乙烷的测定中,采用大口径毛细管柱分离效果优于固定液为10％聚乙二醇填充柱；检测器采用FID优于ECD.结论 该方法重现性佳,分离效果好.
目的 改進明膠空心膠囊中殘留氯乙醇和環氧乙烷的測定方法.方法 採用大口徑毛細管柱代替標準方法中規定的10％聚乙二醇填充柱,檢測器採用FID和TCD,分彆進行測定.結果 對氯乙醇和環氧乙烷的測定中,採用大口徑毛細管柱分離效果優于固定液為10％聚乙二醇填充柱；檢測器採用FID優于ECD.結論 該方法重現性佳,分離效果好.
목적 개진명효공심효낭중잔류록을순화배양을완적측정방법.방법 채용대구경모세관주대체표준방법중규정적10％취을이순전충주,검측기채용FID화TCD,분별진행측정.결과 대록을순화배양을완적측정중,채용대구경모세관주분리효과우우고정액위10％취을이순전충주；검측기채용FID우우ECD.결론 해방법중현성가,분리효과호.
Objective To improve the method for detecting residual chlorine ethylene oxide and ethanol in gelatin hollow capsules.Methods The 10％ polyethylene glycol packed column was replaced by a large caliber capillary column.Detection was conducted with FID and TCD as detectors.Results The large caliber capillary column was superior to the packed column with stationary liquid of 10％ polyethylene glycol in the separation effect.FID was better than ECD for detection.Conclusions This new method has better repeatability and separation effect.
