CAJ | 학술논문

目前临床上常用的监测及评估肾移植术后移植肾功能的方法均有不足之处，而MR扩散成像包括扩散加权成像（DWI）和扩散张量成像(DTI)，能从形态学以及水分子扩散、组织微灌注等微观结构层面无创性地反映组织病理生理变化，在评价肾脏功能方面具有广阔的应用前景。对DWI和DTI在肾脏的应用基础和两者在移植肾功能评价方面的研究进展进行综述。
목전림상상상용적감측급평고신이식술후이식신공능적방법균유불족지처，이MR확산성상포괄확산가권성상（DWI）화확산장량성상(DTI)，능종형태학이급수분자확산、조직미관주등미관결구층면무창성지반영조직병리생리변화，재평개신장공능방면구유엄활적응용전경。대DWI화DTI재신장적응용기출화량자재이식신공능평개방면적연구진전진행종술。
Current methods in clinic have more or less deficiencies in monitoring and evaluating functional abnormalities of transplants after kidney transplantation. Magnetic resonance diffusion imaging, including diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI), can detect pathophysiological changes in tissues not only in morphological level, but also in microstructural level, such as water molecular diffusion and micro-perfusion. Application of DWI and DTI in assessment of renal function has demonstrated broad prospects. This article aims to review both the application basis of DWI and DTI in kidney as well as research progress of DWI and DTI in functional assessment of transplants.