国际医学放射学杂志
國際醫學放射學雜誌
국제의학방사학잡지
INTERNATIONAL JOURNAL OF MEDICAL RADIOLOGY
2014年
4期
307-310,322
,共5页
夏爽%闫铄%柴超%卢光明
夏爽%閆鑠%柴超%盧光明
하상%염삭%시초%로광명
磁敏感征%磁敏感加权成像%血栓%缺血性脑卒中%大脑中动脉
磁敏感徵%磁敏感加權成像%血栓%缺血性腦卒中%大腦中動脈
자민감정%자민감가권성상%혈전%결혈성뇌졸중%대뇌중동맥
Susceptibility vessel sign%Susceptibility weighted imaging%Thrombus%Ischemic stroke%Middle cerebral artery
目的:探讨大脑中动脉(MCA)及其分支血栓对脑组织梗死范围的影响以及栓子的演变过程。方法回顾性分析MR血管成像(MRA)显示的60例一侧MCA主干或分支闭塞的病人资料。根据磁敏感加权成像(SWI)上显示有无磁敏感征(SVS),将病人分为伴有SVS组(41例)和不伴有SVS组(19例)。采用t检验、Mann-Whitney U检验、卡方检验和Fisher确切概率法及单因素方差分析比较伴有和不伴有SWI显示的SVS的病人情况,以及血栓长度对扩散加权成像(DWI)显示的梗死范围的影响,并随访评价采用随机数表法随机抽取的20例伴有SVS病人的栓子的演变。结果2组病人的一般临床资料中性别构成、年龄、房颤、高血脂、糖尿病及血管闭塞侧别比较差异均无统计学意义(均P>0.05)。伴有SVS组病人发病到MRI检查的时间明显短于不伴有SVS组;不伴有SVS组的收缩压和舒张压明显高于伴有SVS组;伴有SVS组的美国国立卫生研究院卒中量表(NIHSS)评分明显高于不伴有SVS 组(均P<0.05)。与不伴有SVS 的病人比较,伴有 SVS 病人的梗死范围较大(P=0.000)。3个级别梗死的血栓长度差异有统计学意义(F=3.338,P=0.04),且1级梗死病人的栓子长度显著大于3级梗死病人的栓子长度(P=0.011)。20例伴有SVS的随访病人中有17例复查时SVS消失,复查时NIHSS评分明显低于最初检查时的评分(t=4.52,P=0.04)。结论 SVS更常见于缺血性病人的急性期,而且可反映血栓的成分。 SVS的存在提示病人的临床情况更差,SVS的消失提示病人预后较好。
目的:探討大腦中動脈(MCA)及其分支血栓對腦組織梗死範圍的影響以及栓子的縯變過程。方法迴顧性分析MR血管成像(MRA)顯示的60例一側MCA主榦或分支閉塞的病人資料。根據磁敏感加權成像(SWI)上顯示有無磁敏感徵(SVS),將病人分為伴有SVS組(41例)和不伴有SVS組(19例)。採用t檢驗、Mann-Whitney U檢驗、卡方檢驗和Fisher確切概率法及單因素方差分析比較伴有和不伴有SWI顯示的SVS的病人情況,以及血栓長度對擴散加權成像(DWI)顯示的梗死範圍的影響,併隨訪評價採用隨機數錶法隨機抽取的20例伴有SVS病人的栓子的縯變。結果2組病人的一般臨床資料中性彆構成、年齡、房顫、高血脂、糖尿病及血管閉塞側彆比較差異均無統計學意義(均P>0.05)。伴有SVS組病人髮病到MRI檢查的時間明顯短于不伴有SVS組;不伴有SVS組的收縮壓和舒張壓明顯高于伴有SVS組;伴有SVS組的美國國立衛生研究院卒中量錶(NIHSS)評分明顯高于不伴有SVS 組(均P<0.05)。與不伴有SVS 的病人比較,伴有 SVS 病人的梗死範圍較大(P=0.000)。3箇級彆梗死的血栓長度差異有統計學意義(F=3.338,P=0.04),且1級梗死病人的栓子長度顯著大于3級梗死病人的栓子長度(P=0.011)。20例伴有SVS的隨訪病人中有17例複查時SVS消失,複查時NIHSS評分明顯低于最初檢查時的評分(t=4.52,P=0.04)。結論 SVS更常見于缺血性病人的急性期,而且可反映血栓的成分。 SVS的存在提示病人的臨床情況更差,SVS的消失提示病人預後較好。
목적:탐토대뇌중동맥(MCA)급기분지혈전대뇌조직경사범위적영향이급전자적연변과정。방법회고성분석MR혈관성상(MRA)현시적60례일측MCA주간혹분지폐새적병인자료。근거자민감가권성상(SWI)상현시유무자민감정(SVS),장병인분위반유SVS조(41례)화불반유SVS조(19례)。채용t검험、Mann-Whitney U검험、잡방검험화Fisher학절개솔법급단인소방차분석비교반유화불반유SWI현시적SVS적병인정황,이급혈전장도대확산가권성상(DWI)현시적경사범위적영향,병수방평개채용수궤수표법수궤추취적20례반유SVS병인적전자적연변。결과2조병인적일반림상자료중성별구성、년령、방전、고혈지、당뇨병급혈관폐새측별비교차이균무통계학의의(균P>0.05)。반유SVS조병인발병도MRI검사적시간명현단우불반유SVS조;불반유SVS조적수축압화서장압명현고우반유SVS조;반유SVS조적미국국립위생연구원졸중량표(NIHSS)평분명현고우불반유SVS 조(균P<0.05)。여불반유SVS 적병인비교,반유 SVS 병인적경사범위교대(P=0.000)。3개급별경사적혈전장도차이유통계학의의(F=3.338,P=0.04),차1급경사병인적전자장도현저대우3급경사병인적전자장도(P=0.011)。20례반유SVS적수방병인중유17례복사시SVS소실,복사시NIHSS평분명현저우최초검사시적평분(t=4.52,P=0.04)。결론 SVS경상견우결혈성병인적급성기,이차가반영혈전적성분。 SVS적존재제시병인적림상정황경차,SVS적소실제시병인예후교호。
Objective To study 1) the relationship between the thrombus in middle cerebral artery (MCA) or its branches and the ishcemic area and 2) the evolution of the thrombus. Methods A total of 60 patients with occlusion of middle cerebral artery or its branches on MR angiography were retrospectively included in our study. According to the presence of susceptibility sign (SVS) or not, the patients were divided into two groups. The SVS, the length of the thrombus on SWI, and range of the ischemic infarction on diffusion weighted imaging (DWI) were evaluated using t test, Mann-Whitney U test, one-way ANOVA, chi-square and Fisher exact test. 20 cases with SVS were selected with a random number table method for followed up study to see the evolution of the thrombus. Result There were no statistical differences in sex, age, presence of atrial fibrillation, hyperlipemia, diabetes, and side of artery occlusion between two groups (all P>0.05). The time from symptom onset to MRI examination was much shorter in patients with SVS than without (P=0.02). The systolic and diastolic blood pressures were statistical higher in patients without SVS than that of with SVS (P<0.05). The NIHSS in patients with SVS was higher than that of without (P=0.01). The infarction extent in patients with SVS was larger than that without(P=0.000). The length of the thrombus in the group with a large infarction was statistically longer than that of the group with the small infarction (P=0.004). In the 20 cases with follow-up MRI, disappearance of SVS on SWI was seen in 17 cases and the NIHSS was decreased compared to that of the initial time (t=4.52,P=0.04). Conclusions The susceptibility vessel sign was much more commonly seen in the acute or sub-acute stage of ischemic stroke. The presence of SVS indicates more severe clinical status and the disappearance of SVS implicates good prognosis.