中国康复理论与实践
中國康複理論與實踐
중국강복이론여실천
CHINESE JOURNAL OF REHABILITATION THEORY & PRACTICE
2014年
7期
659-662
,共4页
于秋红%陈昭燃%刘亚玲%薛连璧
于鞦紅%陳昭燃%劉亞玲%薛連璧
우추홍%진소연%류아령%설련벽
吸氧%听觉诱发电位%P300%潜伏期%振幅
吸氧%聽覺誘髮電位%P300%潛伏期%振幅
흡양%은각유발전위%P300%잠복기%진폭
oxygen inhalation%auditory evoked potential%P300%latency%amplitude
目的：研究吸氧对听觉诱发电位P300潜伏期和振幅的影响。方法健康男性志愿者27例，根据随机数字表分为对照组(n=12)和实验组(n=15)。志愿者均佩戴面罩，对照组呼吸空气，实验组呼吸医用纯氧60 min。应用Oddball双声刺激序列，记录志愿者吸氧前、吸氧20 min、吸氧50 min、吸氧后30 min的闭眼脑电图，计算靶刺激P300潜伏期和电位。结果对照组吸氧前、吸氧20 min、吸氧50 min和吸氧后30 min，P300潜伏期分别为(335.91±15.40) ms、(358.58±15.32) ms、(353.42±9.41) ms和(354.10±10.42) ms， P300潜伏期明显延长(P<0.01)；实验组吸氧前、吸氧后20 min、吸氧50 min和吸氧后30 min， P300潜伏期分别为(332.98±14.63) ms、(326.05±13.53) ms、(319.17±14.34) ms和(318.50±13.87) ms，吸氧50 min和吸氧后30 min与吸氧前相比，P300潜伏期缩短(P<0.05)。吸氧20 min、吸氧50 min和吸氧后30 min时两组比较，实验组比对照组P300潜伏期显明缩短(P<0.01)。对照组P300振幅相对稳定(P<0.05)；实验组振幅逐渐下降，吸氧后30 min为(2.41±0.64)μV，吸氧前为(5.49±0.89)μV，两者相比有显著性差异(P<0.05)。结论吸氧使听觉诱发电位P300潜伏期缩短，振幅减小，而且随吸氧时间延长，这种趋势更明显。
目的：研究吸氧對聽覺誘髮電位P300潛伏期和振幅的影響。方法健康男性誌願者27例，根據隨機數字錶分為對照組(n=12)和實驗組(n=15)。誌願者均珮戴麵罩，對照組呼吸空氣，實驗組呼吸醫用純氧60 min。應用Oddball雙聲刺激序列，記錄誌願者吸氧前、吸氧20 min、吸氧50 min、吸氧後30 min的閉眼腦電圖，計算靶刺激P300潛伏期和電位。結果對照組吸氧前、吸氧20 min、吸氧50 min和吸氧後30 min，P300潛伏期分彆為(335.91±15.40) ms、(358.58±15.32) ms、(353.42±9.41) ms和(354.10±10.42) ms， P300潛伏期明顯延長(P<0.01)；實驗組吸氧前、吸氧後20 min、吸氧50 min和吸氧後30 min， P300潛伏期分彆為(332.98±14.63) ms、(326.05±13.53) ms、(319.17±14.34) ms和(318.50±13.87) ms，吸氧50 min和吸氧後30 min與吸氧前相比，P300潛伏期縮短(P<0.05)。吸氧20 min、吸氧50 min和吸氧後30 min時兩組比較，實驗組比對照組P300潛伏期顯明縮短(P<0.01)。對照組P300振幅相對穩定(P<0.05)；實驗組振幅逐漸下降，吸氧後30 min為(2.41±0.64)μV，吸氧前為(5.49±0.89)μV，兩者相比有顯著性差異(P<0.05)。結論吸氧使聽覺誘髮電位P300潛伏期縮短，振幅減小，而且隨吸氧時間延長，這種趨勢更明顯。
목적：연구흡양대은각유발전위P300잠복기화진폭적영향。방법건강남성지원자27례，근거수궤수자표분위대조조(n=12)화실험조(n=15)。지원자균패대면조，대조조호흡공기，실험조호흡의용순양60 min。응용Oddball쌍성자격서렬，기록지원자흡양전、흡양20 min、흡양50 min、흡양후30 min적폐안뇌전도，계산파자격P300잠복기화전위。결과대조조흡양전、흡양20 min、흡양50 min화흡양후30 min，P300잠복기분별위(335.91±15.40) ms、(358.58±15.32) ms、(353.42±9.41) ms화(354.10±10.42) ms， P300잠복기명현연장(P<0.01)；실험조흡양전、흡양후20 min、흡양50 min화흡양후30 min， P300잠복기분별위(332.98±14.63) ms、(326.05±13.53) ms、(319.17±14.34) ms화(318.50±13.87) ms，흡양50 min화흡양후30 min여흡양전상비，P300잠복기축단(P<0.05)。흡양20 min、흡양50 min화흡양후30 min시량조비교，실험조비대조조P300잠복기현명축단(P<0.01)。대조조P300진폭상대은정(P<0.05)；실험조진폭축점하강，흡양후30 min위(2.41±0.64)μV，흡양전위(5.49±0.89)μV，량자상비유현저성차이(P<0.05)。결론흡양사은각유발전위P300잠복기축단，진폭감소，이차수흡양시간연장，저충추세경명현。
Objective To observe the change of the latency and amplitude of auditory-evoked potential P300 after oxygen inhalation. Methods 27 healthy male academicians were included. They were divided into control group (n=12) and experiment group (n=15) accord-ing to the random numerical table, and they were blinded about groups. All subjects in the experiment group inhaled pure oxygen while air in the control group through a mask for 60 minutes. EEG was recorded when an auditory Oddball paradigm was performed during following 4 periods:before oxygen inhalation (pre0), inhale oxygen (air in control) for 20 minutes (Oxy20) and 50 minutes (Oxy50), 30 minutes after oxygen inhaled (post30). The latency and amplitude of P300 from target stimuli were calculated. Results The latency of P300 was longer at Oxy20 as (358.58±15.32) ms, Oxy50 as (353.42±9.41) ms and post30 as (354.10±10.42) ms than at pre0 as (335.91±15.40) ms in the con-trol group (P<0.01). The latency of P300 was shorter at Oxy50 as (319.17 ± 14.34) ms, and post30 as (318.50 ± 13.87) ms than at pre0 as (332.98±14.63) ms in the experiment group (P<0.05). The latency was shorter in the experiment group than in the control group at Oxy20, Oxy50 and post30 (P<0.01). The amplitudes were stable in the control group (P<0.05). The amplitude was lower at post30 as (2.41 ± 0.64) μV than at pre0 as (5.49±0.89) μV in the experiment group (P<0.05). Conclusion Oxygen inhalation shortens the latency of P300, and de-creases the amplitude in the similar trend with the prolongation of oxygen inhalation.
