CAJ | 학술논문

目的：探讨急性重症胰腺炎患者血脂水平变化及预后不良的危险因素。方法对100例急性重症胰腺炎患者（存活87例，死亡13例）的临床资料进行回顾性分析，测定患者入院后第1天血脂水平。对比分析存活组和死亡组的临床资料，探讨急性重症胰腺炎患者预后不良的危险因素。结果两组性别、CT评分比较，差异无统计学意义（ P＞0．05）。存活组年龄、APACHEⅡ评分、Ranson评分、病程均明显小于或低于死亡组（ P＜0．05）。存活组入院后次日TC、TG均明显低于死亡组（ P＜0．05），而HDL、LDL 差异无统计学意义（ P＞0．05）。非条件logistic回归分析结果显示，年龄大、TG水平高、APACHEⅡ评分高是急性重症胰腺炎患者预后不良的独立危险因素（ P＜0．05）。结论年龄大、TG水平高、APACHEⅡ评分高是急性重症胰腺炎患者预后不良的独立危险因素。
목적：탐토급성중증이선염환자혈지수평변화급예후불량적위험인소。방법대100례급성중증이선염환자（존활87례，사망13례）적림상자료진행회고성분석，측정환자입원후제1천혈지수평。대비분석존활조화사망조적림상자료，탐토급성중증이선염환자예후불량적위험인소。결과량조성별、CT평분비교，차이무통계학의의（ P＞0．05）。존활조년령、APACHEⅡ평분、Ranson평분、병정균명현소우혹저우사망조（ P＜0．05）。존활조입원후차일TC、TG균명현저우사망조（ P＜0．05），이HDL、LDL 차이무통계학의의（ P＞0．05）。비조건logistic회귀분석결과현시，년령대、TG수평고、APACHEⅡ평분고시급성중증이선염환자예후불량적독립위험인소（ P＜0．05）。결론년령대、TG수평고、APACHEⅡ평분고시급성중증이선염환자예후불량적독립위험인소。
Objective To investigate the changes in serum lipid levels and the risk factors for poor prognosis in patients with severe acute pancreatitis .Methods A retrospective analysis was conducted in 100 patients with acute severe pancreatitis ( survival 87 cases and 13 cases died ) , the serum lipid level on the first day after admission was tested .The clinical data of survival group and death group were analyzed to explore the risk factors for poor prognosis in patients with acute severe pancreatitis .Results There was no significant difference in gender and CT score between two groups(P>0.05).The age,APACHEⅡ score,Ranson score and duration in the survival group were significantly smaller or less than those in the death group (P<0.05).On the second day after admission ,TC and TG in the survival group were significantly lower than those in the death group ( P<0 .05 ) ,whereas HDL ,LDL showed no significant difference between two groups (P>0.05).Unconditional logistic regression analysis showed that age ,high TG levels,high APACHEⅡscore were independent risk factors for severe acute pancreatitis patients with poor prognosis (P<0.05).Conclusion Age,high TG levels,high APACHE Ⅱ score are independent risk factor for severe acute pancreatitis patients with poor prognosis .