CAJ | 학술논문

目的：研究急性心肌梗死（AMI）患者再灌注治疗后血浆脑钠肽（BNP）与梗死部位的关系。方法选取50例 AMI 行再灌注治疗的患者，按梗死部位分为急性前壁心肌梗死组（前壁 AMI 组）和急性下壁心肌梗死组（下壁 AMI 组）。监测入院时、再灌注治疗后24 h 及再灌注30 d 血浆 BNP 浓度，分析 BNP 水平与梗死部位的关系。结果前壁 AMI 组与下壁 AMI 组比较，入院时 BNP（BNP0）、再灌注治疗24 h BNP（BNP24）在前壁 AMI 组更高（P <0.05），再灌注治疗后30 d BNP（BNP30）在两组中比较差异无统计学意义（P >0.05）。结论 AMI 再灌注治疗后24 h血浆 BNP 水平在前壁 AMI 患者中较高。
목적：연구급성심기경사（AMI）환자재관주치료후혈장뇌납태（BNP）여경사부위적관계。방법선취50례 AMI 행재관주치료적환자，안경사부위분위급성전벽심기경사조（전벽 AMI 조）화급성하벽심기경사조（하벽 AMI 조）。감측입원시、재관주치료후24 h 급재관주30 d 혈장 BNP 농도，분석 BNP 수평여경사부위적관계。결과전벽 AMI 조여하벽 AMI 조비교，입원시 BNP（BNP0）、재관주치료24 h BNP（BNP24）재전벽 AMI 조경고（P <0.05），재관주치료후30 d BNP（BNP30）재량조중비교차이무통계학의의（P >0.05）。결론 AMI 재관주치료후24 h혈장 BNP 수평재전벽 AMI 환자중교고。
Objective To study the relationship between plasma brain natriuretic peptide ( BNP)and infarction location in acute myocardial infarction( AMI)patients after reperfusion thera-py. Methods Fifty AMI patients undertaken reperfusion therapy were selected. They were divided into acute anterior myocardial infarction group ( anterior AMI group ) and acute inferior myocardial infarct.ion group ( inferior AMI group)according to infarction location. Brain natriuretic peptide(BNP)levels were monitored on admission ,24 hours after reperfusion therapy,30 days after reperfusion. The relationship between plasma brain natriuretic peptide( BNP)level and infarction location were analyzed. Results Comparing acute anterior myocardial infarction(anterior AMI group)and acute inferior myocardial infarction(inferior AMI group), BNP on admission(BNP0),BNP at 24 hours after reperfusion therapy( BNP24)was higher in inferior AMI group(P <0. 05). There was no significant difference in BNP 30 days after reperfusion( BNP30) between the two groups(P >0. 05). Conclusions Plasma BNP leve of 24 hours after AMI reperfusion therapy is higher in anterior acute myocardial infarction patients.