CAJ | 학술논문

目的：评价负压引流结合穿支血管皮瓣移植治疗糖尿病足溃疡的临床疗效。方法选择2006年2月至2013年6月湛江市中心人民医院诊断的晚期糖尿病足患者56例，随机分为治疗组27例和对照组29例。治疗组采用负压引流结合穿支皮瓣修复创面，对照组采用传统换药结合植皮修复。分析比较两组患者皮瓣移植术前的有效率，首次移植完全成活率及住院天数的差异。结果治疗组穿支皮瓣移植术前有效率，首次皮瓣移植手术完全成活率均显著高于对照组，差异有统计学意义（88.9%比44.7%，χ2=9.868，P =0.02；100%比47.4%，χ2=14.122，P <0.001）；治疗组平均住院天数显著少于对照组，差异有统计学意义[（39.3±11.6）比（50.8±21.5），t =-4.178，P =0.039]。结论封闭负压引流结合穿支皮瓣移植是治疗糖尿病足的一种有效治疗方式，能明显增加带蒂皮瓣移植术前创面的愈合率，提高一次皮瓣移植成活率，缩短住院时间。
목적：평개부압인류결합천지혈관피판이식치료당뇨병족궤양적림상료효。방법선택2006년2월지2013년6월담강시중심인민의원진단적만기당뇨병족환자56례，수궤분위치료조27례화대조조29례。치료조채용부압인류결합천지피판수복창면，대조조채용전통환약결합식피수복。분석비교량조환자피판이식술전적유효솔，수차이식완전성활솔급주원천수적차이。결과치료조천지피판이식술전유효솔，수차피판이식수술완전성활솔균현저고우대조조，차이유통계학의의（88.9%비44.7%，χ2=9.868，P =0.02；100%비47.4%，χ2=14.122，P <0.001）；치료조평균주원천수현저소우대조조，차이유통계학의의[（39.3±11.6）비（50.8±21.5），t =-4.178，P =0.039]。결론봉폐부압인류결합천지피판이식시치료당뇨병족적일충유효치료방식，능명현증가대체피판이식술전창면적유합솔，제고일차피판이식성활솔，축단주원시간。
Objective To evaluate the clinical effect of negative pressure drainage combined with penetrating artery flap transplantation on diabetic foot ulcer. Methods From February 2006 to June 2013,56 patients with late stage diabetic foot admitted in our hospital were chosen,and randomly divided into treatment group(27 cases)and control group(29 cases). Patients in treatment group were given negative pressure drainage combined with penetrating artery flap for wound repairment,and the patients in control group were given conventional dressing changes combined with skin-grafting for wound repairment. The effective rate before skin flap transplantation operation,complete survival rate of the first transplantation and hospitalization days between the two groups were analyzed and compared. Results The effective rate before skin flap transplantation operation and complete survival rate of the first transplantation in treatment group was obviously higher than that in control group,there were signifi-cant differences(88. 9% vs 44. 7% ,χ2 = 9. 868,P = 0. 02;100% vs 47. 4% ,χ2 = 14. 122,P < 0. 01);The mean hospitalization days in treatment group were obviously shorter than those in control group,there age combined with penetrating artery flap transplantation is an effective treatment method for diabetic foot,which can obviously increase the healing rate of pedicled skin flap transplantation operation and sur-vival rate of the first skin flap transplantation,as well as shorten the hospitalization days.