中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
13期
48-50
,共3页
慢性阻塞性肺疾病急性加重%脑钠肽%Tei 指数%右心功能
慢性阻塞性肺疾病急性加重%腦鈉肽%Tei 指數%右心功能
만성조새성폐질병급성가중%뇌납태%Tei 지수%우심공능
Acute exacerbation of chronic obstructive pulmonary disease%Brain natriuretic peptide%Tei index%Right ventricular function
目的：探讨联合检测脑钠肽（BNP）及心脏 Tei 指数对评估慢性阻塞性肺疾病急性加重期（AECOPD）患者右心功能的临床应用价值。方法71例 AECOPD 患者按有无合并左心衰竭分为左心衰组和非左心衰组，对照组30例。用 ELISA 方法检测血浆 BNP 水平，超声心动图测量心脏 Tei 指数，并进行比较；对 AECOPD 患者治疗前后上述指标进行比较。结果①两组 AECOPD 患者治疗前血浆 BNP 水平及心脏 Tei 指数均较对照组显著升高（P <0.01），且左心衰组血浆 BNP 水平及心脏 Tei 指数高于非左心衰组（P <0.01）。②治疗后两组 AECOPD 患者BNP 及心脏 Tei 指数均较治疗前下降（P <0.01）。③AECOPD 患者血浆 BNP 与心脏 Tei 指数均呈正相关。结论联合检测 BNP 及心脏彩超 Tei 指数可早期评估 AECOPD 患者右心功能情况，评估疗效及预后。
目的：探討聯閤檢測腦鈉肽（BNP）及心髒 Tei 指數對評估慢性阻塞性肺疾病急性加重期（AECOPD）患者右心功能的臨床應用價值。方法71例 AECOPD 患者按有無閤併左心衰竭分為左心衰組和非左心衰組，對照組30例。用 ELISA 方法檢測血漿 BNP 水平，超聲心動圖測量心髒 Tei 指數，併進行比較；對 AECOPD 患者治療前後上述指標進行比較。結果①兩組 AECOPD 患者治療前血漿 BNP 水平及心髒 Tei 指數均較對照組顯著升高（P <0.01），且左心衰組血漿 BNP 水平及心髒 Tei 指數高于非左心衰組（P <0.01）。②治療後兩組 AECOPD 患者BNP 及心髒 Tei 指數均較治療前下降（P <0.01）。③AECOPD 患者血漿 BNP 與心髒 Tei 指數均呈正相關。結論聯閤檢測 BNP 及心髒綵超 Tei 指數可早期評估 AECOPD 患者右心功能情況，評估療效及預後。
목적：탐토연합검측뇌납태（BNP）급심장 Tei 지수대평고만성조새성폐질병급성가중기（AECOPD）환자우심공능적림상응용개치。방법71례 AECOPD 환자안유무합병좌심쇠갈분위좌심쇠조화비좌심쇠조，대조조30례。용 ELISA 방법검측혈장 BNP 수평，초성심동도측량심장 Tei 지수，병진행비교；대 AECOPD 환자치료전후상술지표진행비교。결과①량조 AECOPD 환자치료전혈장 BNP 수평급심장 Tei 지수균교대조조현저승고（P <0.01），차좌심쇠조혈장 BNP 수평급심장 Tei 지수고우비좌심쇠조（P <0.01）。②치료후량조 AECOPD 환자BNP 급심장 Tei 지수균교치료전하강（P <0.01）。③AECOPD 환자혈장 BNP 여심장 Tei 지수균정정상관。결론연합검측 BNP 급심장채초 Tei 지수가조기평고 AECOPD 환자우심공능정황，평고료효급예후。
Objective To study the clinical application value of combined detection of brain na-triuretic peptide( BNP)and Tei index on evaluating right ventricular function in acute exacerbation of chronic obstructive pulmonary disease(AECOPD). Methods Seventy-one AECOPD patients were di-vided into two groups:left heart failure group and non left heart failure group,with 30 cases in each group. The serum BNP concentration was obtained using enzyme immunoassay before and after treatment respectively. The right ventricular Tei index was also calculated. Thirty normal subjects were studied as controls. Results ① Compared with control values,the serum BNP concentrations and Tei indexes were significantly elevated in AECOPD patients(P < 0. 01). They also obviously raised in left heart failure group than non left heart failure group.(P < 0. 01). ② After treatment,BNP and Tei index decreased re-markablely(P < 0. 01). ③ The BNP levels were positively correlated with Tei indexs in AECOPD. Con-clusions Combined detection of BNP and Tei index is useful for early assessment of right ventricular function,the curative effect and prognosis in AECOPD.
