CAJ | 학술논문

目的：分析遗传性多发性骨软骨瘤（HME）的99m Tc - MDP 全身骨显像的影像特点，评价骨显像在 HME 中的应用价值。方法分析74例确诊为 HME 患者的临床、骨显像资料，总结 HME 的骨显像特点。结果74例患者中，肿瘤好发部位位于长骨的干骺端，颅面骨未见发现，主要表现为长骨干骺端骨质增粗，以膝关节周围表现最为明显；在所有病灶中，未见放射性摄取减低病灶（0级）。全身骨显像共显示371个病灶，其中1级摄取病灶占全部病灶的8.6%（32/371），2级摄取病灶占全部病灶的34.2%（127/371），3级摄取病灶占全部病灶的39.6%（147/371），4级摄取病灶占全部病灶的17.5%（65/371）。结论 HME 的全身骨显像表现为长骨末端异常的、不规则的、多处的放射性浓聚，结合临床及其他影像学资料，99m Tc - MDP 全身骨显像可用于 HME 患者的诊断与鉴别诊断、随访以及肿瘤恶变的评价。
목적：분석유전성다발성골연골류（HME）적99m Tc - MDP 전신골현상적영상특점，평개골현상재 HME 중적응용개치。방법분석74례학진위 HME 환자적림상、골현상자료，총결 HME 적골현상특점。결과74례환자중，종류호발부위위우장골적간후단，로면골미견발현，주요표현위장골간후단골질증조，이슬관절주위표현최위명현；재소유병조중，미견방사성섭취감저병조（0급）。전신골현상공현시371개병조，기중1급섭취병조점전부병조적8.6%（32/371），2급섭취병조점전부병조적34.2%（127/371），3급섭취병조점전부병조적39.6%（147/371），4급섭취병조점전부병조적17.5%（65/371）。결론 HME 적전신골현상표현위장골말단이상적、불규칙적、다처적방사성농취，결합림상급기타영상학자료，99m Tc - MDP 전신골현상가용우 HME 환자적진단여감별진단、수방이급종류악변적평개。
Objective To investigate the usefulness of 99Tcm - MDP whole body bone scintigraphy(WBBS)in patients with Hereditary multiple exostoses HME. Methods 99m Tc - MDP WBBS was performed in 74 patients with HME. The typical scintigraphic manifestations of He-reditary multiple exostoses HME were summarized. Results Bone scintigraphy found that the most common location of exostosis was juxta -epiphyscal regions of the long bones among 74 patients,showed bone thickening. The change around the knee joint was the most obvious. No exos-tosis was found in skull. In all lesions,1 grade of uptake accounted for8. 6% of all lesions(32 / 371),2 grade of uptake lesions accounted for 34. 2 of all lesions(127 / 371),3 uptake lesions accounted for 39. 6% of all lesions(147 / 371),four pickup lesions account for all lesions of 17. 5%(65 / 371). Conclusion Hereditary multiple exostoses showed irregular various radioactive concentration in end of long bones,99Tcm - MDP bone scintigraphy which combined with clinical and radiological data can be used to diagnose,differentiate,and localize the insidious lesion and e-valuate the tumor malignant transformation in patients with HME.