CAJ | 학술논문

目的：探讨肝动脉化疗栓塞（TACE）序贯精确放疗对原发性肝癌的患者的治疗效果。方法收集进行非手术疗法治疗的原发性肝癌的患者40例，按照就诊的先后顺序随机分为观察组及对照组，每组各20例患者。对照组采用 TACE 的方法进行治疗，观察组在此基础上联合应用精确放疗的方法进行治疗。4周后对比两组的治疗效果。结果两组采取的治疗方法都有不同程度地抑制病情进展的作用。对照组的近期有效率为45.0%，观察组为75.0%，观察组的近期有效率显著高于对照组，差异具有统计学意义（ P ﹤0.05）。观察组治疗后甲胎蛋白低于对照组，差异具有统计学意义（ P ﹤0.05）。结论 TACE 序贯精确放疗的方法对原发性肝癌的治疗有重要意义，可以有效地控制肿瘤的生长，对肝脏进行一定程度的保护。
목적：탐토간동맥화료전새（TACE）서관정학방료대원발성간암적환자적치료효과。방법수집진행비수술요법치료적원발성간암적환자40례，안조취진적선후순서수궤분위관찰조급대조조，매조각20례환자。대조조채용 TACE 적방법진행치료，관찰조재차기출상연합응용정학방료적방법진행치료。4주후대비량조적치료효과。결과량조채취적치료방법도유불동정도지억제병정진전적작용。대조조적근기유효솔위45.0%，관찰조위75.0%，관찰조적근기유효솔현저고우대조조，차이구유통계학의의（ P ﹤0.05）。관찰조치료후갑태단백저우대조조，차이구유통계학의의（ P ﹤0.05）。결론 TACE 서관정학방료적방법대원발성간암적치료유중요의의，가이유효지공제종류적생장，대간장진행일정정도적보호。
Objective To investigate and study the therapeutic effect of TACE sequential combined with precise radiotherapy on patients with primary liver cancer. Methods 40 cases of primary liver cancer patients treated with non - surgical therapy in our hospital were divided into two groups according to the treatment order,that was observation group and control group,20 cases in each group. The control group was given TACE sequential therapy,while the observation group applied precise radiotherapy on the basis of observation group. The course of treatment was 4 weeks. The treatment efficacy of two groups was compared. Results Different treatment methods of two groups could inhibit the progress of dis-ease in different degrees. The immediate effective rate of control group(45. 0% )was lower than that of the observation group(75. 0% ),which indicated that the immediate effective rate of observation group was significantly higher than the control group. When compared the alpha fetal pro-tein(AFP)cases of two groups. There was statistical significance( P ﹤ 0. 05),which indicated that for the protection of the liver. The observa-tion group was better than the control group. Conclusion TACE sequential precise radiotherapy plays an important role in the treatment of primary liver cancer,which can control the growth of tumors effectively and protect the liver to a certain degree.