CAJ | 학술논문

目的：观察鼓室灌注联合静脉注射地塞米松治疗突发性耳聋的临床效果。方法将76例（76耳）突发性耳聋患者随机分为 A、B 两组，各38例，其中 A 组予静滴地塞米松，辅以鼓室注射地塞米松。B 组则单纯按照 A 组的静脉用药方法。观察两组患者治疗前后平均听阈值变化及两组有效率情况。结果 A 组平均听阈治疗前后分别为（70.24±15.28）dB 和（51.28±21.26）dB；B 组平均听阈治疗前后分别为（70.35±16.27）dB 和（60.17±24.32）dB。A组患者平均听阈改善程度明显优于 B 组（ P ﹤0.05）。A 组治疗总有效率为94.7%高于 B 组78.9%（ P ﹤0.05）。结论
목적：관찰고실관주연합정맥주사지새미송치료돌발성이롱적림상효과。방법장76례（76이）돌발성이롱환자수궤분위 A、B 량조，각38례，기중 A 조여정적지새미송，보이고실주사지새미송。B 조칙단순안조 A 조적정맥용약방법。관찰량조환자치료전후평균은역치변화급량조유효솔정황。결과 A 조평균은역치료전후분별위（70.24±15.28）dB 화（51.28±21.26）dB；B 조평균은역치료전후분별위（70.35±16.27）dB 화（60.17±24.32）dB。A조환자평균은역개선정도명현우우 B 조（ P ﹤0.05）。A 조치료총유효솔위94.7%고우 B 조78.9%（ P ﹤0.05）。결론
Objective To observe the clinical effect of intratympanic dexamethasone perfusion in the treatment of sudden deafness. Methods Thirty - eight subjects(thirty - eight ears)were divided into two groups randomly,including group A(38 subjects;38 ears)and group B(38 sub-jects,38 ears). The patients in treatment group A were given intravenous infusion of dexamethasone,combined with perfusion of dexamethasone into the tympanum. The control group simply applied intravenous infusion of dexamethasone. The efficiency and the average hearing threshold changes of two groups before and after treatment was observed. Results Before and after treatment,the average hearing threshold was(70. 24 ±15. 28)dB and (51. 28 ±21. 26)dB in the treatment group. And the average hearing threshold was(70. 35 ± 16. 27)dB and(60. 17 ± 24. 32)dB in the control group. The clinical effect of the group A was significantly better than the group B( P ﹤0. 05). The effective rate of group A(94. 7% )was signifi-cantly higher than that of the group B(78. 9% ). There was no obvious adverse reaction and complication in two groups. Conclusion The treatment for sudden deafness with dual pathways combined with hormone can improve the clinical efficacy for the treatment of sudden deafness therapy.