CAJ | 학술논문

目的：观察激光治疗不同分期糖尿病视网膜病变（DR）的临床疗效。方法收集糖尿病性视网膜病变患者300例共408眼，根据眼底荧光素血管造影分为增殖前期（PPDR）246眼和增殖期（PDR）两组162眼。对两组糖尿病视网膜病变患者均行全视网膜光凝术。对比分析两组治疗后的视力及视野、眼底荧光造影（FFA）检查的结果。结果全视网膜光凝术后，PPDR 组视力提高81眼（32.9%），PDR 组视力提高37眼（22.8%），PPDR 组视力提高者比率优于PDR 组，差异有统计学意义（ P ﹤0.05）；复查 FFA 情况，PPDR 组有效率90.7%显著高于 PDR 组的79.6%，差异有统计学意义（ P ﹤0.05）；PPDR 和 PDR 两组的黄斑阈值敏感度变化手术前后比较均无显著性差异，而术后中心30°视野平均阈值敏感度均下降。结论早期进行视网膜光凝术虽对视野有一定损害，但仍可以保持或提高 DR 患者视功能。
목적：관찰격광치료불동분기당뇨병시망막병변（DR）적림상료효。방법수집당뇨병성시망막병변환자300례공408안，근거안저형광소혈관조영분위증식전기（PPDR）246안화증식기（PDR）량조162안。대량조당뇨병시망막병변환자균행전시망막광응술。대비분석량조치료후적시력급시야、안저형광조영（FFA）검사적결과。결과전시망막광응술후，PPDR 조시력제고81안（32.9%），PDR 조시력제고37안（22.8%），PPDR 조시력제고자비솔우우PDR 조，차이유통계학의의（ P ﹤0.05）；복사 FFA 정황，PPDR 조유효솔90.7%현저고우 PDR 조적79.6%，차이유통계학의의（ P ﹤0.05）；PPDR 화 PDR 량조적황반역치민감도변화수술전후비교균무현저성차이，이술후중심30°시야평균역치민감도균하강。결론조기진행시망막광응술수대시야유일정손해，단잉가이보지혹제고 DR 환자시공능。
Objective To analyze the effect of laser photocoagulation in treating diabetic retinopathy(DR). Methods 300 cases(408 eyes )of inpatient and outpatient diabetic retinopathy patients were divided into two groups,preproliferative diabetic group(PPDR)and prolifera-tive diabetic retinopathy group(PDR). The two groups were treated by laser photocoagulation. The results of vision,visual fields and fundus fluo-rescein angiography(FFA)were analyzed. The period of postoperation follow up was 1year. Results In all patients with panretinal photocoagula-tion,vision was improved in 81 eyes in PPDR group and in 37 eyes in PDR group( P ﹤ 0. 05). After one time panretinal photocoagulation,the effective rate was 90. 7% in group of PPDR and 79. 6% in PDR group. There was statistical difference between the two groups. And there were decrease in MTS in these two groups. Conclusion Panretinal photocoagulation in the early stage can significantly improve and keep the visual function of patients with diabetic retinopathy.