CAJ | 학술논문

目的：了解社区医师医院感染经验性抗菌药物选择的准确性与药敏报告后抗菌药物的调整情况，以指导临床合理使用抗菌药物。方法回顾性分析我中心2011年1月-2013年5月119例医院感染患者病原体培养阳性结果，分析经验性抗菌药物选择的准确性及药敏报告后抗菌药物的调整情况。结果经验性抗菌药物使用的准确性仅为48.7%（58/119），抗菌药物经验性选择与药敏试验相符的病例感染治疗有效率较高，达93.1%（54/58），而不相符的病例虽及时调整抗菌药物，其有效率仅为68.9%（42/61）。结论医院感染正确的初始抗菌药物治疗对患者的预后有重要意义，社区医生对医院感染患者经验性选择抗菌药物准确性偏低，应引起重视。
목적：료해사구의사의원감염경험성항균약물선택적준학성여약민보고후항균약물적조정정황，이지도림상합리사용항균약물。방법회고성분석아중심2011년1월-2013년5월119례의원감염환자병원체배양양성결과，분석경험성항균약물선택적준학성급약민보고후항균약물적조정정황。결과경험성항균약물사용적준학성부위48.7%（58/119），항균약물경험성선택여약민시험상부적병례감염치료유효솔교고，체93.1%（54/58），이불상부적병례수급시조정항균약물，기유효솔부위68.9%（42/61）。결론의원감염정학적초시항균약물치료대환자적예후유중요의의，사구의생대의원감염환자경험성선택항균약물준학성편저，응인기중시。
Objective To understand the accuracy of empirical selection of antimicrobial against hospital infection by community doctors and adjustment of antimicrobial after the Drug susceptibility report to guide the clinical rational use of antimi-crobial. Methods The positive results of microbial cultivation among 119 cases of patients with nosocomial infection in our center (January 2011-May 2013)were retrospectively analyzed in terms of the accuracy of empirical selection and the adjustment of an-timicrobial after the drug susceptibility report. Results Accuracy of empirical antimicrobial drug use was only 48. 7%( 58/119),Cases in empirical selection of antimicrobial conformed to the drug susceptibility had a higher curative efficiency,up to 93. 1%(54/58). The efficiency of the otherwise cases was only 68. 9%(42/61),although having made an immediate adjust-ment of antimicrobial. Conclusion The correct initial hospital infection antimicrobial therapy is significant for the prognosis of the patients. Low accuracy of community doctors' empirical selection of antimicrobial against nosocomial infection should arouse our higher attention.