CAJ | 학술논문

目的研究替加环素联合美罗培南治疗广泛耐药鲍曼不动杆菌感染的疗效及安全性.方法采用回顾性调查的方法,对2012年2-12月广东省惠州市中心医院重症医学科泛耐药鲍曼不动杆菌感染患者采用替加环素联合美罗培南治疗的疗效及安全性进行分析.结果广泛耐药鲍曼不动杆菌感染患者共10例.其中男性8例,女性2例,呼吸机相关性肺炎7例,泌尿系感染2例,血流性感染1例.替加环素联合美罗培南治疗时间7～21 d,总有效率100％.共有4例出现不良反应,其中2例出现嗜睡,1例发生腹泻,1例出现轻度黄疸.全部患者均能耐受治疗.结论替加环素联合美罗培南用于治疗广泛耐药鲍曼不动杆菌感染安全有效.
목적 연구체가배소연합미라배남치료엄범내약포만불동간균감염적료효급안전성.방법 채용회고성조사적방법,대2012년2-12월광동성혜주시중심의원중증의학과범내약포만불동간균감염환자채용체가배소연합미라배남치료적료효급안전성진행분석.결과 엄범내약포만불동간균감염환자공10례.기중남성8례,녀성2례,호흡궤상관성폐염7례,비뇨계감염2례,혈류성감염1례.체가배소연합미라배남치료시간7～21 d,총유효솔100％.공유4례출현불량반응,기중2례출현기수,1례발생복사,1례출현경도황달.전부환자균능내수치료.결론 체가배소연합미라배남용우치료엄범내약포만불동간균감염안전유효.
Objective To analyze the efficacy and safety of tigecycline combined meropenem in treatment of extensively drug resistant acinetobacter baumannii.Methods Ten cases of extensively drug resistant acinetobacter baumannii infections treated with tigecycline combined meropenem were retrospectively analyzed from February 2012 to December 2012.Results All 10 patients infection of extensively drug resistant acinetobacter baumannii included 8 men and 2 women,7 cases were ventilator associated pneumonia,2 cases were urinary system infections,1 case was blood infection,the treatment time was 7-21 days,the total effective rate was 100.0％,2 cases had sleepiness,1 case had diarrhea,one case had mild jaundice,all patients could tolerate the treatment.Conclusions It is effective and safe to use tigecycline combined meropenem treating of extensively drug resistant acinetobacter baumannii infections.