CAJ | 학술논문

目的：了解老年炎症性肠病（IBD）患者的生存质量（QOL）及影响因素。方法采用问卷调查法，对消化内科门诊及病房收治的老年患者100例进行一般资料及生存质量的横断面调查，应用中文IBgQ、SF-36、焦虑自评量表、抑郁自评量表、简易应对方式问卷、社会支持评定量表，通过相关分析和多元回归分析，筛选出影响IBD患者QOL的主要因素。结果100例老年IBD患者中溃疡性结肠炎（ UC）者72例，克罗恩病（ CD）者28例，其中两组参与研究入选者相比，人口学特征无显著差异；所有IBD患者的IBDQ总评分为148.85±26.31，肠道症状得分为48.85±8.69，全身症状得分为20.96±5.43，情感功能得分为54.46±10.29，社会功能得分为21.78±5.97，所有维度得分均处于中等水平；UC 患者与 CD患者在各维度得分均比较接近，且都处于中等水平，两组患者的QOL之间无明显差异（P＞0.05）；老年IBD患者与健康对照组QOL比较，结果显示各维度得分均低于健康对照组（P＜0.05）；不同文化程度、职业的IBD患者QOL的差别有统计学意义（P＜0.05）。高学历患者 SF-36的心理、社会领域的评分明显低于低学历患者（ P＜0.05）；重型IBD患者在IBDQ和SF-36总分及其他各维度得分均低于轻型患者（ P＜0.05）；积极应对、社会支持等得分与QOL得分呈正相关（P＜0.05）；焦虑、抑郁、消极应对得分与生存质量得分呈负相关（P＜0.05）。多元回归分析显示，抑郁、焦虑、病情、文化程度、病期是影响IBD患者生存质量的相关因素。结论病情重的IBD患者的生存质量较低；焦虑、抑郁水平越高，患者的生存质量越低。 IBD患者主要在心理健康方面受到影响。
목적：료해노년염증성장병（IBD）환자적생존질량（QOL）급영향인소。방법채용문권조사법，대소화내과문진급병방수치적노년환자100례진행일반자료급생존질량적횡단면조사，응용중문IBgQ、SF-36、초필자평량표、억욱자평량표、간역응대방식문권、사회지지평정량표，통과상관분석화다원회귀분석，사선출영향IBD환자QOL적주요인소。결과100례노년IBD환자중궤양성결장염（ UC）자72례，극라은병（ CD）자28례，기중량조삼여연구입선자상비，인구학특정무현저차이；소유IBD환자적IBDQ총평분위148.85±26.31，장도증상득분위48.85±8.69，전신증상득분위20.96±5.43，정감공능득분위54.46±10.29，사회공능득분위21.78±5.97，소유유도득분균처우중등수평；UC 환자여 CD환자재각유도득분균비교접근，차도처우중등수평，량조환자적QOL지간무명현차이（P＞0.05）；노년IBD환자여건강대조조QOL비교，결과현시각유도득분균저우건강대조조（P＜0.05）；불동문화정도、직업적IBD환자QOL적차별유통계학의의（P＜0.05）。고학력환자 SF-36적심리、사회영역적평분명현저우저학력환자（ P＜0.05）；중형IBD환자재IBDQ화SF-36총분급기타각유도득분균저우경형환자（ P＜0.05）；적겁응대、사회지지등득분여QOL득분정정상관（P＜0.05）；초필、억욱、소겁응대득분여생존질량득분정부상관（P＜0.05）。다원회귀분석현시，억욱、초필、병정、문화정도、병기시영향IBD환자생존질량적상관인소。결론병정중적IBD환자적생존질량교저；초필、억욱수평월고，환자적생존질량월저。 IBD환자주요재심리건강방면수도영향。
Objective To understand the inflammatory bowel disease ( IBD ) patients ’ quality of life ( QOL ) influencing fac-tors.Methods Questionnaire was used to collect 100 patients ’ data including general information and living quality of the cross-sectional survey by application Chinese IBgQ , SF-36, self rating anxiety scale , self rating depression scale , simple coping style questionnaire , social support rating scale.Correlation analysis and multiple regression analysis were used to screen out the main factors affecting the IBD of pa -tients with QOL.Results There were 72 cases of UC and 28 cases of CD in 100 IBD patients and there was no significant differences in the demographic between the two groups.Total IBDQ score was 148.85 ±26.31 , intestinal tract symptoms score 48.85 ±8.69 , systemic symp-tom score 20.96 ±5.43 , emotion functional score 54.46 ±10.29 , social function score 21.78 ±5.97 of all IBD patients , and all scores were in the medium level.UC patients and CD patients were relatively close to the score of each dimension , and were in the medium level , there were no significant differences in quality of survival between two groups of patients.Elderly IBD patients ’ scores were lower than those of the healthy controls ( P<0.05 ).There were significant differences among different culture degree and occupation IBD patients .Scores of high degree patients in psychological , social domain score of SF-36 were significantly lower than those of low degree ( P<0.05 ).IBDQ and SF-36 scores of patients with severe IBD were lower than those of light IBD patients ( P<0.05 ).Positive coping , social support score and quality of life scores were positively correlated (P<0.05).Anxiety, depression, negative coping style and quality of life scores were nega-tively correlated (P<0.05).Multiple regression analysis showed that depression , anxiety, illness, disease stage, culture degree were the re-lated factors influencing the life quality of patients with IBD.Conclusions The severity of life quality of IBD patients is low , the higher the level of anxiety and depression , the lower quality of life.IBD patients mainly are affected in terms of mental health .