CAJ | 학술논문

目的：探讨重症新生儿高胆红素血症同步换血治疗前后实验室检测意义。方法：收集重症新生儿高胆红素血症同步换血治疗患儿43例，在换血治疗前后分别采集血液进行电解质、血常规、胆红素指标检测，并比较治疗前后各指标的变化。结果：经换血治疗后总胆红素、直接胆红素、间接胆红素、白细胞、血小板、钾、钙较治疗前明显下降，治疗前后比较差异有统计学意义（P＜0.01）；红细胞较治疗前有所升高，治疗前后差异有统计学意义（P＜0.01）；血红蛋白、钠、氯治疗后与治疗前比较差异无统计学意义（P＞0.05）。结论：同步换血治疗是治疗重症新生儿高胆红素血症安全有效的治疗手段，为临床提供有效的检测数据。
목적：탐토중증신생인고담홍소혈증동보환혈치료전후실험실검측의의。방법：수집중증신생인고담홍소혈증동보환혈치료환인43례，재환혈치료전후분별채집혈액진행전해질、혈상규、담홍소지표검측，병비교치료전후각지표적변화。결과：경환혈치료후총담홍소、직접담홍소、간접담홍소、백세포、혈소판、갑、개교치료전명현하강，치료전후비교차이유통계학의의（P＜0.01）；홍세포교치료전유소승고，치료전후차이유통계학의의（P＜0.01）；혈홍단백、납、록치료후여치료전비교차이무통계학의의（P＞0.05）。결론：동보환혈치료시치료중증신생인고담홍소혈증안전유효적치료수단，위림상제공유효적검측수거。
Objective To explore the effect of exchange transfusion in severe neonatal hyperbilirubinemia by available laboratory tests. Methods 43 neonates with severe hyperbilirubinemia were treated by exchange transfusion, and compared the changes of the index with electrolyte, blood routine and bilirubin on pretherapy and post-treatment. Results Compared to pretherapy, the level of total bilirubin, direct bilirubin, indirect bilirubin, white blood cel s, platelets count, potassium, calcium decreased significantly (P<0.01), red blood cel s level increased significantly (P<0.01), and the index of hemoglobin, sodium and chloride was no significant difference (P>0.05). Conclusions Exchange transfusion is a safe and effective treatment for neonates with severe hyperbilirubinemia, and it could provide the effective test data.