CAJ | 학술논문

目的：了解本地区围产儿出生缺陷的发生情况，及时发现影响出生缺陷的可疑因素，为制定干预措施提供依据。方法按照国家出生缺陷监测方案的要求，对2006年10月1日～2011年9月30日在六合区有产科的医院出生的、孕满28周至产后7天内的32562例围产儿进行监测。结果出生缺陷儿171例，出生缺陷儿发生率为5.25‰；出生缺陷的发生与环境因素、孕母年龄、出生性别等有关。结论进行优生优育宣传指导，为孕妇创造优良的生育环境及合理的均衡饮食，提高产前诊断技术，适时终止妊娠，可有效降低出生缺陷发生率。
목적：료해본지구위산인출생결함적발생정황，급시발현영향출생결함적가의인소，위제정간예조시제공의거。방법안조국가출생결함감측방안적요구，대2006년10월1일～2011년9월30일재륙합구유산과적의원출생적、잉만28주지산후7천내적32562례위산인진행감측。결과출생결함인171례，출생결함인발생솔위5.25‰；출생결함적발생여배경인소、잉모년령、출생성별등유관。결론진행우생우육선전지도，위잉부창조우량적생육배경급합리적균형음식，제고산전진단기술，괄시종지임신，가유효강저출생결함발생솔。
Objective :in this study, we monitored and analyzed the perinatal birth defect in Luhe district, Nanjing in order to promptly establish proper measures to control this disease.Methods: According to the national birth defect monitoring protocol, 32562 perinatal samples during 28 weeks after pregnancy and 7 days after born were monitored. The term was from October 1, 2006 to September 30, 2011. The data were colected from al the hospitals or centers in Luhe district.Results: the monitoring results showed that 171 cases were diagnosed birth defect. The ratio was 5.25‰. It related to multi-influence factors including environment, maternal’s age on perinatal outcomes and baby gender etc.Conclusions:The perinatal birth defect could be controled efficiently by several ways, such as folowing the pregnant quality guideline, providing good environments to pregnant women, and improving the pre-pregnant diagnosis in terminal pregnancy.