CAJ | 학술논문

【目的】探讨维C银翘片红外光谱学特性，为其质量控制提供参考。【方法】采用红外光谱法对广西盈康药业生产的10个不同批号维C银翘片进行检测，并以其平均图谱为标准图谱（即标准图谱为1）检测各样品的相似度。【结果】获得维C银翘片红外特征吸收峰；维C银翘片与维生素 C及与对乙酰氨基酚对照品三者的共有红外特征吸收峰；维生素C与对乙酰氨基酚的检识红外特征吸收峰；10批样品的相似度在0．9941～0．9993，拟定其阈值为0．9900。【结论】所建立的方法具有简便、快速、灵敏等特点，可为维 C银翘片的定性鉴别及其处方中的维生素C与对乙酰氨基酚检识提供参考。
【목적】탐토유C은교편홍외광보학특성，위기질량공제제공삼고。【방법】채용홍외광보법대엄서영강약업생산적10개불동비호유C은교편진행검측，병이기평균도보위표준도보（즉표준도보위1）검측각양품적상사도。【결과】획득유C은교편홍외특정흡수봉；유C은교편여유생소 C급여대을선안기분대조품삼자적공유홍외특정흡수봉；유생소C여대을선안기분적검식홍외특정흡수봉；10비양품적상사도재0．9941～0．9993，의정기역치위0．9900。【결론】소건립적방법구유간편、쾌속、령민등특점，가위유 C은교편적정성감별급기처방중적유생소C여대을선안기분검식제공삼고。
Objective]The characteristics of infrared spectroscopy of vitamin C Yinqiao tablets were investigated in order to provide reference for its quality control.[Methods]Detection of 1 0 different batches of vitamin C Yinqiao tablets produced by Guangxi Yingkang Pharmaceutical Company using infrared spectroscopy,and its average spectrum was served as the standard atlas (i.e.standard atlas 1)to detect the similarity of each sample.[Results]The infrared character-istic absorption peaks were obtained from Vc Yinqiao tablets,which were characterized with the three common infrared characteristic absorption peaks among Vc Yinqiao tablets,Vc and acet-aminophen-control products,and for detecting both Vc and acetaminophen.The results showed that the similarity of 10 samples ranged from 0.9941 to 0.9993,formulated the threshold of 0. 9900.[Conclusion]This experiment method is simple,rapid,sensitive,which can provide refer-ence for qualitative identification of the Vc Yinqiao tablets and detection of Vc and acetaminophen in the prescription.