法医学杂志
法醫學雜誌
법의학잡지
JOURNAL OF FORENSIC MEDICINE
2014年
3期
178-180
,共3页
刘冬梅%周姝%陈捷敏%彭书雅%夏文涛
劉鼕梅%週姝%陳捷敏%彭書雅%夏文濤
류동매%주주%진첩민%팽서아%하문도
法医学%中毒%甲醇%视网膜电图%振荡电位%大鼠
法醫學%中毒%甲醇%視網膜電圖%振盪電位%大鼠
법의학%중독%갑순%시망막전도%진탕전위%대서
forensic medicine%poisoning%methanol%electroretinogram%oscillatory potentials%rats
目的:研究大鼠甲醇中毒后视网膜电图(electroretinogram,ERG)振荡电位(oscillatory potentials, OPs)的变化特点。方法建立对照组及甲醇中毒3 d组、中毒7 d组的SD大鼠模型,在相应时间点于暗室内进行ERG检测,记录OPs波形特点。结果相对于对照组,中毒3 d组和中毒7 d组的总振幅均下降了约50%,时程分别延长约16%和61%。结论大鼠甲醇中毒后,ERG的OPs呈现时程延长、总振幅下降特点。
目的:研究大鼠甲醇中毒後視網膜電圖(electroretinogram,ERG)振盪電位(oscillatory potentials, OPs)的變化特點。方法建立對照組及甲醇中毒3 d組、中毒7 d組的SD大鼠模型,在相應時間點于暗室內進行ERG檢測,記錄OPs波形特點。結果相對于對照組,中毒3 d組和中毒7 d組的總振幅均下降瞭約50%,時程分彆延長約16%和61%。結論大鼠甲醇中毒後,ERG的OPs呈現時程延長、總振幅下降特點。
목적:연구대서갑순중독후시망막전도(electroretinogram,ERG)진탕전위(oscillatory potentials, OPs)적변화특점。방법건립대조조급갑순중독3 d조、중독7 d조적SD대서모형,재상응시간점우암실내진행ERG검측,기록OPs파형특점。결과상대우대조조,중독3 d조화중독7 d조적총진폭균하강료약50%,시정분별연장약16%화61%。결론대서갑순중독후,ERG적OPs정현시정연장、총진폭하강특점。
Objective To study the characters of oscillatory potentials (OPs) of electroretinogram (ERG) after methanol intoxication in rats. Method The SD rat models of methanol intoxication were established and divided into control group, 3-day intoxication group, 7-day intoxication group. The changes of OPs of ERG were recorded in a dark room. Results The total amplitudes of 3-day and 7-day intoxication groups decreased approximately 50% compared with that of the control group, while the schedule de-layed approximately 16% and 61%, respectively. Conclusion The characters of methanol intoxication in rats included delay in schedule and decline in the total amplitude of OPs.