CAJ | 학술논문

目的：探讨溃疡汤联合三联疗法治疗幽门螺杆菌（Hp）感染消化性溃疡的临床疗效。方法将60例消化性溃疡患者按治疗方法的不同分为2组：观察组和对照组，每组30例。2组均适当休息，进清淡流质饮食或低脂、少渣半流质饮食或软食，忌烟、酒及辛辣食物，同时采用奥美拉唑、甲硝唑和克拉霉素治疗。2周后，改为奥美拉唑治疗。在此基础上，观察组采用溃疡汤治疗。观察2组的临床疗效及不良反应情况。结果观察组总有效率、Hp 根除率均明显高于对照组（96.67%、96.67%比76.67%、80.00%，均P＜0.05）。结论溃疡汤联合三联疗法治疗Hp感染消化性溃疡有利于提高临床疗效及Hp根除率，显著地改善患者的临床症状，促进溃疡愈合，且无明显的不良反应。
목적：탐토궤양탕연합삼련요법치료유문라간균（Hp）감염소화성궤양적림상료효。방법장60례소화성궤양환자안치료방법적불동분위2조：관찰조화대조조，매조30례。2조균괄당휴식，진청담류질음식혹저지、소사반류질음식혹연식，기연、주급신랄식물，동시채용오미랍서、갑초서화극랍매소치료。2주후，개위오미랍서치료。재차기출상，관찰조채용궤양탕치료。관찰2조적림상료효급불량반응정황。결과관찰조총유효솔、Hp 근제솔균명현고우대조조（96.67%、96.67%비76.67%、80.00%，균P＜0.05）。결론궤양탕연합삼련요법치료Hp감염소화성궤양유리우제고림상료효급Hp근제솔，현저지개선환자적림상증상，촉진궤양유합，차무명현적불량반응。
Objective To observe the clinical effects of ulceration soup combined with triple therapy on Helicobacter pylori(Hp)-associated peptic ulcer. Methods Sixty patients with peptic ulcer were divided into observation group and control group,with 30 patients in each group. All patients received routine management of peptic ulcer,including proper rest,bland liquid diet,low-fat and low residue semi-liquid diet or soft diet, and avoiding tobacco, alcohol and spicy foods.At the same time, patients were treated with omeprazole,metronidazole and clarithromycin. After two weeks,patients were treated with omeprazole only.In addition, patients in observation group were given ulceration soup. Curative effects and adverse reactions were observed in both groups. Results Compared with control group, the total effective rate and Hp eradication rate significantly increased in observation group (96.67% and 96.67% vs 76.67% and 80.00%, respectively; P<0.05). Conclusion Ulceration soup combined with triple therapy increases Hp eradication rate, improves clinical symptoms, promotes ulcer healing, and does not cause obvious adverse reactions in the treatment of Hp-associated peptic ulcer.