光谱学与光谱分析
光譜學與光譜分析
광보학여광보분석
SPECTROSCOPY AND SPECTRAL ANALYSIS
2014年
7期
2005-2009
,共5页
林凌%李威%曾锐利%刘瑞安%李刚%吴晓荣
林凌%李威%曾銳利%劉瑞安%李剛%吳曉榮
림릉%리위%증예리%류서안%리강%오효영
试验方差分析%血氧饱和度测量%波长选取%光电容积脉搏波
試驗方差分析%血氧飽和度測量%波長選取%光電容積脈搏波
시험방차분석%혈양포화도측량%파장선취%광전용적맥박파
The analysis of variance%Oximetry%Wavelength selection%Photoplethysmography (PPG)
为了提高血氧饱和度光谱测量的精度和可靠性,增强血氧饱和度测量数据的有效性,提出了基于试验方差分析的血氧测量波长选取的方法。通过分析不同波长组合对应的血氧饱和度系数分布情况,合理地利用统计理论,从中选取较好的波长组合。实验中以不同血氧饱和度临床数据为基础,建立了不同波长组合(660和940 nm ,660和805 nm ,805和940 nm )计算出的血氧饱和度系数的单因素试验方差分析模型,参照分析模型中的 F指标和p参数,比较分析不同波长组合的显著性,进而从光谱数据中选取出相对较好的波长组合,为进一步建模分析提供了可靠的中间数据。结果表明,选取660和805 nm的波长组合引入的总误差相对较小,能更显著的代表血氧饱和度的变化,相比其他的波长组合进行分析能够提高血氧测量精度。本研究将试验方差分析方法用于血氧测量中波长组合的优选,效果显著,为血氧饱和度的测量和其他相关光谱的特征波长选取以及定量分析提供了新思路。试验方差分析方法有助于从光谱中提取代表被测量的有效信息。
為瞭提高血氧飽和度光譜測量的精度和可靠性,增彊血氧飽和度測量數據的有效性,提齣瞭基于試驗方差分析的血氧測量波長選取的方法。通過分析不同波長組閤對應的血氧飽和度繫數分佈情況,閤理地利用統計理論,從中選取較好的波長組閤。實驗中以不同血氧飽和度臨床數據為基礎,建立瞭不同波長組閤(660和940 nm ,660和805 nm ,805和940 nm )計算齣的血氧飽和度繫數的單因素試驗方差分析模型,參照分析模型中的 F指標和p參數,比較分析不同波長組閤的顯著性,進而從光譜數據中選取齣相對較好的波長組閤,為進一步建模分析提供瞭可靠的中間數據。結果錶明,選取660和805 nm的波長組閤引入的總誤差相對較小,能更顯著的代錶血氧飽和度的變化,相比其他的波長組閤進行分析能夠提高血氧測量精度。本研究將試驗方差分析方法用于血氧測量中波長組閤的優選,效果顯著,為血氧飽和度的測量和其他相關光譜的特徵波長選取以及定量分析提供瞭新思路。試驗方差分析方法有助于從光譜中提取代錶被測量的有效信息。
위료제고혈양포화도광보측량적정도화가고성,증강혈양포화도측량수거적유효성,제출료기우시험방차분석적혈양측량파장선취적방법。통과분석불동파장조합대응적혈양포화도계수분포정황,합리지이용통계이론,종중선취교호적파장조합。실험중이불동혈양포화도림상수거위기출,건립료불동파장조합(660화940 nm ,660화805 nm ,805화940 nm )계산출적혈양포화도계수적단인소시험방차분석모형,삼조분석모형중적 F지표화p삼수,비교분석불동파장조합적현저성,진이종광보수거중선취출상대교호적파장조합,위진일보건모분석제공료가고적중간수거。결과표명,선취660화805 nm적파장조합인입적총오차상대교소,능경현저적대표혈양포화도적변화,상비기타적파장조합진행분석능구제고혈양측량정도。본연구장시험방차분석방법용우혈양측량중파장조합적우선,효과현저,위혈양포화도적측량화기타상관광보적특정파장선취이급정량분석제공료신사로。시험방차분석방법유조우종광보중제취대표피측량적유효신식。
In order to improve the precision and reliability of the spectral measurement of blood oxygen saturation ,and enhance the validity of the measurement ,the method of test analysis of variance was employed .Preferred wavelength combination was selected by the analysis of the distribution of the coefficient of oximetry at different wavelength combinations and rational use of statistical theory .Calculated by different combinations of wavelengths (660 and 940 nm ,660 and 805 nm and 805 and 940 nm) through the clinical data under different oxygen saturation ,the single factor test analysis of variance model of the oxygen satura-tion coefficient was established ,the relative preferabe wavelength combination can be selected by comparative analysis of differ-ent combinations of wavelengths from the photoelectric volume pulse to provide a reliable intermediate data for further modeling . The experiment results showed that the wavelength combination of 660 and 805 nm responded more significantly to the changes in blood oxygen saturation and the introduced noise and method error were relatively smaller of this combination than other wave-length combination ,which could improve the measurement accuracy of oximetry .The study applied the test variance analysis to the selection of wavelength combination in the blood oxygen result measurement ,and the result was significant .The study pro-vided a new idea for the blood oxygen measurements and other related spectroscopy quantitative analysis .The method of test a-nalysis of variance can help extract the valid information which represents the measured values from the spectrum .