医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
16期
41-42
,共2页
无创呼吸机%联合%纳洛酮%老年%COPD%呼吸衰竭%疗效
無創呼吸機%聯閤%納洛酮%老年%COPD%呼吸衰竭%療效
무창호흡궤%연합%납락동%노년%COPD%호흡쇠갈%료효
noninvasive ventilator%joint%naloxon%e elderly%COPD%respiratory failure%efficacy
目的：研究无创呼吸机联合纳洛酮治疗老年阻塞性肺病的临床效果。方法选取2010年3月～2013年2月间入院诊治的老年COPD合并呼吸衰竭的患者120例，随机分为实验组（60例）和对照组（60例），其中对照组单纯应用无创呼吸机治疗，实验组在对照组基础上联合纳洛酮治疗。疗程结束后观察两组患者的治疗效果及呼吸、心率、动脉血气指标等。结果实验组显效25例，好转29例，总有效率为90.00%；对照组显效15例，好转30例，总有效率为75.00%。两组患者PaO2、PaCO2、PH、SpO2等动脉血气指标与治疗前相比均有所改善，且实验组疗效更优。上述数据均具有统计学意义（P<0.05）。结论无创呼吸机联合纳洛酮治疗老年阻塞性肺疾病具有良好的疗效，可显著改善动脉血气指标，提高患者的生活质量。
目的：研究無創呼吸機聯閤納洛酮治療老年阻塞性肺病的臨床效果。方法選取2010年3月～2013年2月間入院診治的老年COPD閤併呼吸衰竭的患者120例，隨機分為實驗組（60例）和對照組（60例），其中對照組單純應用無創呼吸機治療，實驗組在對照組基礎上聯閤納洛酮治療。療程結束後觀察兩組患者的治療效果及呼吸、心率、動脈血氣指標等。結果實驗組顯效25例，好轉29例，總有效率為90.00%；對照組顯效15例，好轉30例，總有效率為75.00%。兩組患者PaO2、PaCO2、PH、SpO2等動脈血氣指標與治療前相比均有所改善，且實驗組療效更優。上述數據均具有統計學意義（P<0.05）。結論無創呼吸機聯閤納洛酮治療老年阻塞性肺疾病具有良好的療效，可顯著改善動脈血氣指標，提高患者的生活質量。
목적：연구무창호흡궤연합납락동치료노년조새성폐병적림상효과。방법선취2010년3월～2013년2월간입원진치적노년COPD합병호흡쇠갈적환자120례，수궤분위실험조（60례）화대조조（60례），기중대조조단순응용무창호흡궤치료，실험조재대조조기출상연합납락동치료。료정결속후관찰량조환자적치료효과급호흡、심솔、동맥혈기지표등。결과실험조현효25례，호전29례，총유효솔위90.00%；대조조현효15례，호전30례，총유효솔위75.00%。량조환자PaO2、PaCO2、PH、SpO2등동맥혈기지표여치료전상비균유소개선，차실험조료효경우。상술수거균구유통계학의의（P<0.05）。결론무창호흡궤연합납락동치료노년조새성폐질병구유량호적료효，가현저개선동맥혈기지표，제고환자적생활질량。
Objective To study the clinical effects of non-invasive ventilation combined with naloxone to elderly patients with obstructive pulmonary disease. Methods 120 elderly COPD patients with respiratory failure hospitalized from March 2010 -February 2013 were randomly divided into experimental group (60 cases) and control group (60 cases). The control group were treated with non-invasive respiratory machine treatment, and the experimental group were based on the combination of both non-invasive respiratory machine and naloxone. Respiration, heart rate, arterial blood gas were utilized as indicators of therapeutic effects of both groups. Results 25 cases with significant effects were observed in experimental group, as wel as 29 cases with relative effects , the total effective rate was 90.00%; 15 cases with significant effects were observed in control group, as wel as 30 cases with relative effects, the total effective rate was 75.00%. PaO2, PaCO2, PH, SpO2 and other indicators of arterial blood gases were al improved in both groups after treatment, with better efficacy in experimental group. Al data were statistical y significant (P <0.05). Conclusion non-invasive ventilation combined naloxone has good efficacy in theating senile obstructive pulmonary disease and in ameliorating arterial blood gas indicators ,, which consequently contributes to better life quality.
