医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
16期
17-18
,共2页
肺表面活性物质%早产儿%呼吸窘迫综合征
肺錶麵活性物質%早產兒%呼吸窘迫綜閤徵
폐표면활성물질%조산인%호흡군박종합정
Pulmonary surfactant%preterm children%respiratory distress syndrome
目的：探讨肺表面活性物质治疗早产儿呼吸窘迫综合征的临床疗效。方法：选取2012年6月至2013年5月我院收治的早产儿呼吸窘迫综合征患者72例进行分析，按照治疗方法分成观察组和对照组各36例，对照组采用常规治疗，观察组在对照组基础上加用肺表面活性物质治疗，观察两组临床疗效、氧合指数（P a O2/F i O2）、机械通气使用率、吸氧时间、住院时间、并发症发生率和病死率。结果：观察组治疗总有效率明显高于对照组（P＜0.05）；两组治疗后PaO2/FiO2均有明显提高（P＜0.05），且观察组提高水平明显优于对照组（P＜0.05）；观察组机械通气使用率、并发症发生率明显低于对照组（P＜0.05），吸氧时间和住院时间明显少于对照组（P＜0.05）；两组在病死率上比较无明显差异（P＞0.05）。结论：肺表面活性物质治疗早产儿呼吸窘迫综合征能够提高患儿的治愈率，缓解临床症状，降低并发症发生率，安全有效。
目的：探討肺錶麵活性物質治療早產兒呼吸窘迫綜閤徵的臨床療效。方法：選取2012年6月至2013年5月我院收治的早產兒呼吸窘迫綜閤徵患者72例進行分析，按照治療方法分成觀察組和對照組各36例，對照組採用常規治療，觀察組在對照組基礎上加用肺錶麵活性物質治療，觀察兩組臨床療效、氧閤指數（P a O2/F i O2）、機械通氣使用率、吸氧時間、住院時間、併髮癥髮生率和病死率。結果：觀察組治療總有效率明顯高于對照組（P＜0.05）；兩組治療後PaO2/FiO2均有明顯提高（P＜0.05），且觀察組提高水平明顯優于對照組（P＜0.05）；觀察組機械通氣使用率、併髮癥髮生率明顯低于對照組（P＜0.05），吸氧時間和住院時間明顯少于對照組（P＜0.05）；兩組在病死率上比較無明顯差異（P＞0.05）。結論：肺錶麵活性物質治療早產兒呼吸窘迫綜閤徵能夠提高患兒的治愈率，緩解臨床癥狀，降低併髮癥髮生率，安全有效。
목적：탐토폐표면활성물질치료조산인호흡군박종합정적림상료효。방법：선취2012년6월지2013년5월아원수치적조산인호흡군박종합정환자72례진행분석，안조치료방법분성관찰조화대조조각36례，대조조채용상규치료，관찰조재대조조기출상가용폐표면활성물질치료，관찰량조림상료효、양합지수（P a O2/F i O2）、궤계통기사용솔、흡양시간、주원시간、병발증발생솔화병사솔。결과：관찰조치료총유효솔명현고우대조조（P＜0.05）；량조치료후PaO2/FiO2균유명현제고（P＜0.05），차관찰조제고수평명현우우대조조（P＜0.05）；관찰조궤계통기사용솔、병발증발생솔명현저우대조조（P＜0.05），흡양시간화주원시간명현소우대조조（P＜0.05）；량조재병사솔상비교무명현차이（P＞0.05）。결론：폐표면활성물질치료조산인호흡군박종합정능구제고환인적치유솔，완해림상증상，강저병발증발생솔，안전유효。
Objective : To investigate the pulmonary surfactant treatment of respiratory distress syndrome in premature children 's clinical efficacy. Methods: June 2012 to May 2013 in our hospital with respiratory distress syndrome in premature children 72 patients were analyzed according to the treatment methods into observation group and the control group , 36 cases in the control group using conventional treatment, the observation group control group based on the use of pulmonary surfactant therapy , clinical efficacy , oxygenation index (PaO2/FiO2), utilization of mechanical ventilation , oxygen time , hospital stay, morbidity and mortality. Results: The total effective rate was significantly higher (P <0.05); PaO2/FiO2 after treatment were significantly increased (P <0.05), and raise the level of the observation group than the control group (P <0.05 ) ; observe the usage of mechanical ventilation , the complication rate was significantly lower than the control group (P <0.05), oxygen and hospital stay was significantly less than the control group (P <0.05); mortality in the two groups showed no significant difference (P> 0.05). Conclusion: Pulmonary surfactant treatment of respiratory distress syndrome in premature children can improve the cure rate in children , relieve symptoms and reduce the incidence of complications , safe and effective.
