CAJ | 학술논문

目的：探讨埃索美拉唑联合铝碳酸镁﹑多潘立酮治疗胃食管反流性咳嗽的临床疗效。方法选取2012年1月至2013年12月48例反流性慢性咳嗽的患者，随机分为治疗组和对照组，治疗组给予埃索美拉唑﹑多潘立酮﹑铝碳酸镁联合治疗，对照组给予埃索美拉唑﹑多潘立酮联合治疗，根据临床效果进行统计学分析。结果治疗组慢性咳嗽症状改善的有效率96.7％，对照组有效率86.7％；治疗组胃镜下食管炎愈合的有效率93.3％，对照组有效率86.7％，两者比较差异均有统计学意义(P＜0.05)。结论埃索美拉唑﹑多潘立酮﹑铝碳酸镁的三联方案治疗胃食管反流性咳嗽的疗效优于埃索美拉唑及多潘立酮的两联方案。
목적：탐토애색미랍서연합려탄산미﹑다반립동치료위식관반류성해수적림상료효。방법선취2012년1월지2013년12월48례반류성만성해수적환자，수궤분위치료조화대조조，치료조급여애색미랍서﹑다반립동﹑려탄산미연합치료，대조조급여애색미랍서﹑다반립동연합치료，근거림상효과진행통계학분석。결과치료조만성해수증상개선적유효솔96.7％，대조조유효솔86.7％；치료조위경하식관염유합적유효솔93.3％，대조조유효솔86.7％，량자비교차이균유통계학의의(P＜0.05)。결론애색미랍서﹑다반립동﹑려탄산미적삼련방안치료위식관반류성해수적료효우우애색미랍서급다반립동적량련방안。
Objective To explore the clinical curative effect of esomeprazole combined hydrotalcite and domperidone in treatment of gastroesophageal reflux cough . Meathods Choose 48 cases with chronic reflux cough patients between January 2012 and December 2012,they were divided into treatment group and control group randomly , the treatment group were given esomeprazole combined hydrotalcite and domperidone, the control group were given esomeprazole and domperidone only, then made statistical analysis according to the clinical effect.Results The improve effective rate of chronic cough symptoms was 96.7% in treatment group, and 86.7% in control group ; The healing effective rate of esophagitis under gastroscope was 93.3%in treatment group , and 86.7% in control group, both comparative differences are statistical y significant (P < 0.05).Conclution The curative effect of treatment of gastroesophageal reflux cough through esomeprazole combined hydrotalcite and domperidone is better than the esomeprazole and domperidone.