CAJ | 학술논문

为探讨水产养殖中氟喹诺酮类药物残留对水生生物的毒性效应，研究了盐酸恩诺沙星对蛋白核小球藻（Chlorella pyrenoidosa）的急性毒性。结果显示，各药物质量浓度组对蛋白核小球藻的生长均有抑制作用，并且随药物处理质量浓度的增大，藻细胞的生长逐渐降低，显示出明显的剂量-效应关系。盐酸恩诺沙星对蛋白核小球藻的24，48，72，96 h 的 EC50值分别为184.83，341.07，457.84，171.38μg/mL，叶绿素a和b的含量随着盐酸恩诺沙星处理质量浓度的增大呈现相同的变化趋势。
위탐토수산양식중불규낙동류약물잔류대수생생물적독성효응，연구료염산은낙사성대단백핵소구조（Chlorella pyrenoidosa）적급성독성。결과현시，각약물질량농도조대단백핵소구조적생장균유억제작용，병차수약물처리질량농도적증대，조세포적생장축점강저，현시출명현적제량-효응관계。염산은낙사성대단백핵소구조적24，48，72，96 h 적 EC50치분별위184.83，341.07，457.84，171.38μg/mL，협록소a화b적함량수착염산은낙사성처리질량농도적증대정현상동적변화추세。
In order to study the toxic effect of ftuoroquinolones on fresh algae,Chlorella pyre-noidosa was exposed to Enrofloxacin hydrochloride of five concentrations (15.625,31.25,50, 62.5 and 125μg/mL).Results showed that Enrofloxacin hydrochloride had inhibition effect on the growth of Chlorella pyrenoidosa.With the increase of concentration,the inhibition increased correspondingly.The 24,48,72 and 96 h EC50 values of Enrofloxacin hydrochloride were 184.83, 341.07,457.84 and 171.38μg/mL respectively.Enrofloxacin hydrochloride had the same effect on the contents of chlorophyll-a and chlorophyll-b.